JNK2 抗体
(Mitogen-Activated Protein Kinase 9 (MAPK9))
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008].
recommended
recommended
recommended
MAPK9 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 1C1-3A8 unconjugated
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Find JNK2 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
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Cat. No.
ABIN293094
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Latest Publications for our JNK2 抗体
: "IL-33 Attenuates Sepsis by Inhibiting IL-17 Receptor Signaling through Upregulation of SOCS3." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 42, Issue 5, pp. 1961-1972, (2017) (PubMed).: "Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 19, Issue 2, pp. 222-32, (2011) (PubMed).
: "In vivo role of p38 mitogen-activated protein kinase in mediating the anti-inflammatory effects of CpG oligodeoxynucleotide in murine asthma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 10, pp. 5955-61, (2002) (PubMed).
: "A novel mitogen-activated protein kinase is responsive to Raf and mediates growth factor specificity." in: Molecular and cellular biology, Vol. 21, Issue 6, pp. 2235-47, (2001) (PubMed).
: "Involvement of the MAP kinase pathways in induction of GADD45 following UV radiation." in: Experimental cell research, Vol. 269, Issue 1, pp. 64-72, (2001) (PubMed).
: "Diverse functions of JNK signaling and c-Jun in stress response and apoptosis." in: Oncogene, Vol. 18, Issue 45, pp. 6158-62, (1999) (PubMed).
: "Selective interaction of JNK protein kinase isoforms with transcription factors." in: The EMBO journal, Vol. 15, Issue 11, pp. 2760-70, (1996) (PubMed).
: "JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation." in: Genes & development, Vol. 8, Issue 24, pp. 2996-3007, (1995) (PubMed).
: "Signal transduction by tumor necrosis factor mediated by JNK protein kinases." in: Molecular and cellular biology, Vol. 14, Issue 12, pp. 8376-84, (1994) (PubMed).
Aliases for JNK2 抗体
mitogen-activated protein kinase 9 (MAPK9) 抗体mitogen-activated protein kinase 9 (Mapk9) 抗体
MAP kinase 9 (MPK9) 抗体
AI851083 抗体
JNK-55 抗体
JNK2 抗体
JNK2-ALPHA1 抗体
JNK2A 抗体
JNK2ALPHA 抗体
JNK2B 抗体
JNK2BETA 抗体
MAPK9 抗体
MAP kinase 9 抗体
p54a 抗体
p54aSAPK 抗体
PRKM9 抗体
Prkm9 抗体
SAPK 抗体
SAPK1a 抗体
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