JNK2 产品
(Mitogen-Activated Protein Kinase 9 (MAPK9))
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008].
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Featured JNK2 Categories
JNK2 抗体
High quality antibodies with extensive validation data.
JNK2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
JNK2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended JNK2 抗体
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ABIN519243
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ABIN562413
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Recommended JNK2 ELISA试剂盒
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ABIN6957863
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Latest Publications for our JNK2 Products
: "IL-33 Attenuates Sepsis by Inhibiting IL-17 Receptor Signaling through Upregulation of SOCS3." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 42, Issue 5, pp. 1961-1972, (2017) (PubMed).: "JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis." in: PLoS ONE, Vol. 9, Issue 1, pp. e87067, (2014) (PubMed).
: "Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 19, Issue 2, pp. 222-32, (2011) (PubMed).
: "In vivo role of p38 mitogen-activated protein kinase in mediating the anti-inflammatory effects of CpG oligodeoxynucleotide in murine asthma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 10, pp. 5955-61, (2002) (PubMed).
: "A novel mitogen-activated protein kinase is responsive to Raf and mediates growth factor specificity." in: Molecular and cellular biology, Vol. 21, Issue 6, pp. 2235-47, (2001) (PubMed).
: "Involvement of the MAP kinase pathways in induction of GADD45 following UV radiation." in: Experimental cell research, Vol. 269, Issue 1, pp. 64-72, (2001) (PubMed).
: "Diverse functions of JNK signaling and c-Jun in stress response and apoptosis." in: Oncogene, Vol. 18, Issue 45, pp. 6158-62, (1999) (PubMed).
: "Selective interaction of JNK protein kinase isoforms with transcription factors." in: The EMBO journal, Vol. 15, Issue 11, pp. 2760-70, (1996) (PubMed).
: "JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation." in: Genes & development, Vol. 8, Issue 24, pp. 2996-3007, (1995) (PubMed).
: "Signal transduction by tumor necrosis factor mediated by JNK protein kinases." in: Molecular and cellular biology, Vol. 14, Issue 12, pp. 8376-84, (1994) (PubMed).
Synonyms and alternative names related to JNK2
mitogen-activated protein kinase 9 (MAPK9), mitogen-activated protein kinase 9 (Mapk9), MAP kinase 9 (MPK9), AI851083, JNK-55, JNK2, JNK2-ALPHA1, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, MAPK9, MAP kinase 9, p54a, p54aSAPK, PRKM9, Prkm9, SAPK, SAPK1aProtein level used designations for JNK2
- mitogen-activated protein kinase 9
- Jun kinase
- MAP kinase 9
- MAPK 9
- c-Jun N-terminal kinase 2
- c-Jun kinase 2
- stress-activated protein kinase 1a
- stress-activated protein kinase JNK2
- JNK/SAPK alpha
- mitogen activated protein kinase 9
- protein kinase, mitogen-activated 9
- SAPK-alpha
- p54-alpha
- stress activated protein kinase alpha II
- janus kinase 2
- c-JUN amino-terminal kinase-2 alpha1
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