JMJD2D 产品
(Lysine (K)-Specific Demethylase 4D (KDM4D))
Categories
Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys- 9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate (By similarity).
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Featured JMJD2D Categories
Recommended JMJD2D 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IHC
Validations
- (3)
Cat. No.
ABIN7002265
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN6736292
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7158704
Quantity
100 μg
Datasheet
Datasheet
Recommended JMJD2D 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Baculovirus
Validations
- (3)
Cat. No.
ABIN2669707
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308301
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3082371
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our JMJD2D Products
: "JMJD2 promotes acquired cisplatin resistance in non-small cell lung carcinoma cells." in: Oncogene, Vol. 38, Issue 28, pp. 5643-5657, (2019) (PubMed).: "Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors." in: American journal of translational research, Vol. 6, Issue 3, pp. 236-47, (2014) (PubMed).
: "Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following γ-irradiation." in: The Journal of biological chemistry, Vol. 288, Issue 29, pp. 21376-88, (2013) (PubMed).
: "Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D." in: PLoS ONE, Vol. 7, Issue 4, pp. e34618, (2012) (PubMed).
: "Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 49, pp. E3367-76, (2012) (PubMed).
: "Identification and characterization of JMJD2 family genes in silico." in: International journal of oncology, Vol. 24, Issue 6, pp. 1623-8, (2004) (PubMed).
Synonyms and alternative names related to JMJD2D
lysine demethylase 4D (KDM4D), lysine-specific demethylase 4D (LOC524768), lysine (K)-specific demethylase 4D (Kdm4d), lysine-specific demethylase 4D (LOC617971), lysine-specific demethylase 4D (LOC100067461), lysine demethylase 4D (Kdm4d), lysine-specific demethylase 4D (LOC698455), lysine (K)-specific demethylase 4D (KDM4D), lysine-specific demethylase 4D (LOC100514356), 4932416A15, JMJD2D, Jmjd2d, KDM4DProtein level used designations for JMJD2D
- jmjC domain-containing histone demethylation protein 3D
- jumonji domain containing 2D
- jumonji domain-containing protein 2D
- lysine-specific demethylase 4D
- lysine (K)-specific demethylase 4D
- lysine-specific demethylase 4D-like
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