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ITPR3 产品

(Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3))

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This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. [provided by RefSeq, Aug 2010].

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Featured ITPR3 Categories

ITPR3 抗体

High quality antibodies with extensive validation data.

ITPR3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ITPR3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (8)
Cat. No. ABIN3031328
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN3043863
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7239113
Quantity 200 μL
Datasheet Datasheet

Recommended ITPR3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7421836
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ITPR3 Products

Velázquez, Enos, Carson, Cranford, Bader, Sougiannis, Pritchett, Fan, Carson, Murphy: "miR155 deficiency aggravates high-fat diet-induced adipose tissue fibrosis in male mice." in: Physiological reports, Vol. 5, Issue 18, (2018) (PubMed).

Futatsugi, Nakamura, Yamada, Ebisui, Nakamura, Uchida, Kitaguchi, Takahashi-Iwanaga, Noda, Aruga, Mikoshiba: "IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism." in: Science (New York, N.Y.), Vol. 309, Issue 5744, pp. 2232-4, (2005) (PubMed).

Leite, Thrower, Echevarria, Koulen, Hirata, Bennett, Ehrlich, Nathanson: "Nuclear and cytosolic calcium are regulated independently." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 5, pp. 2975-80, (2003) (PubMed).

Zanner, Hapfelmeier, Gratzl, Prinz: "Intracellular signal transduction during gastrin-induced histamine secretion in rat gastric ECL cells." in: American journal of physiology. Cell physiology, Vol. 282, Issue 2, pp. C374-82, (2002) (PubMed).

Pin, Rukstalis, Johnson, Konieczny: "The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity." in: The Journal of cell biology, Vol. 155, Issue 4, pp. 519-30, (2001) (PubMed).

Maranto: "Primary structure, ligand binding, and localization of the human type 3 inositol 1,4,5-trisphosphate receptor expressed in intestinal epithelium." in: The Journal of biological chemistry, Vol. 269, Issue 2, pp. 1222-30, (1994) (PubMed).

Blondel, Takeda, Janssen, Seino, Bell: "Sequence and functional characterization of a third inositol trisphosphate receptor subtype, IP3R-3, expressed in pancreatic islets, kidney, gastrointestinal tract, and other tissues." in: The Journal of biological chemistry, Vol. 268, Issue 15, pp. 11356-63, (1993) (PubMed).

Synonyms and alternative names related to ITPR3

inositol 1,4,5-triphosphate receptor 3 (Itpr3), inositol 1,4,5-trisphosphate receptor type 3 (ITPR3), inositol 1,4,5-trisphosphate receptor, type 3 (Itpr3), IP3R, Ip3r3, IP3R3, IP3R3X, Itpr-3

Protein level used designations for ITPR3

  • IP3 receptor
  • IP3R 3
  • inositol 1,4,5-trisphosphate receptor type 3
  • insP3R3
  • type 3 InsP3 receptor
  • type 3 inositol 1,4,5-trisphosphate receptor
  • inositol 1,4,5-triphosphate receptor, type 3
  • IP3R-3
  • inositol 1,4,5-triphosphate receptor 3
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