ITPR1 产品
(Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))
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This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009].
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Recommended ITPR1 抗体
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Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
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- (1)
- (6)
Cat. No.
ABIN3043862
Quantity
100 μg
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Human
Application
IHC, WB, IF
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- (5)
Cat. No.
ABIN7101690
Quantity
20 μL
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Human
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ELISA, IHC, IF
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- (3)
Cat. No.
ABIN7156293
Quantity
100 μg
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Recommended ITPR1 蛋白
Latest Publications for our ITPR1 Products
: "Inositol 1,4,5-triphosphate receptor is selectively expressed in cerebellum but not cerebellum-like structures of the elasmobranch fish, Leucoraja erinacea." in: Heliyon, Vol. 5, Issue 1, pp. e01176, (2019) (PubMed).: "BAP1 regulates IP3R3-mediated Ca(2+) flux to mitochondria suppressing cell transformation. ..." in: Nature, Vol. 546, Issue 7659, pp. 549-553, (2017) (PubMed).
: "Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta." in: PLoS genetics, Vol. 12, Issue 7, pp. e1006156, (2016) (PubMed).
: "Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP₃ receptor 1 promotes Ca²⁺ signaling in T cells." in: Science signaling, Vol. 7, Issue 345, pp. ra93, (2014) (PubMed).
: "Quantitative proteomic profiling reveals novel region-specific markers in the adult mouse brain." in: Proteomics, Vol. 14, Issue 2-3, pp. 241-61, (2014) (PubMed).
: "Divergent signaling mechanisms for venous versus arterial contraction as revealed by endothelin-1." in: Journal of vascular surgery, (2014) (PubMed).
: "Abolished InsP3R2 function inhibits sweat secretion in both humans and mice." in: The Journal of clinical investigation, Vol. 124, Issue 11, pp. 4773-80, (2014) (PubMed).
: "Microdomains of muscarinic acetylcholine and Ins(1,4,5)P? receptors create 'Ins(1,4,5)P? junctions' and sites of Ca²+ wave initiation in smooth muscle." in: Journal of cell science, Vol. 125, Issue Pt 22, pp. 5315-28, (2013) (PubMed).
: "Fragmented inositol 1,4,5-trisphosphate receptors retain tetrameric architecture and form functional Ca2+ release channels." in: The Journal of biological chemistry, Vol. 288, Issue 16, pp. 11122-34, (2013) (PubMed).
: "Proteomic analysis of primary cultured rat cortical neurons in chemical ischemia." in: Neurochemical research, Vol. 38, Issue 8, pp. 1648-60, (2013) (PubMed).
Synonyms and alternative names related to ITPR1
inositol 1,4,5-trisphosphate receptor type 1 (ITPR1), inositol 1,4,5-trisphosphate receptor 1 (Itpr1), inositol 1,4,5-trisphosphate receptor, type 1 (Itpr1), D6Pas2, ENSMUSG00000072853, Gm10429, I145TR, InsP3R, InsP3R1, INSP3R1, Ip3r, IP3R, IP3R1, Itpr-1, opt, P400, Pcp-1, Pcp1, SCA15, SCA16, SCA29Protein level used designations for ITPR1
- inositol 1,4,5-triphosphate receptor, type 1
- type I inositol triphosphate receptor
- IP3 receptor
- IP3R 1
- InsP3R type I
- InsP>3
- Purkinje cell protein 1
- inositol 1,4,5-triphosphate receptor 1
- inositol 1,4,5-trisphosphate receptor type 1
- inositol 1,4,5-trisphosphate-binding protein P400
- insP3R1
- opisthotonus
- protein PCD-6
- type 1 InsP3 receptor
- type 1 inositol 1,4,5-trisphosphate receptor
- IP-3-R
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