ITPK1 抗体
(Inositol-Tetrakisphosphate 1-Kinase (ITPK1))
Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain (By similarity). Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway.
recommended
recommended
recommended
ITPK1 抗体 by 应用范围
Find ITPK1 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
ITPK1 抗体 by 抗体来源
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ITPK1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal ITPK1 抗体. Click on a link to go to the corresponding products.
ITPK1 抗体 by 克隆
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Popular ITPK1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN517270
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (4)
Cat. No.
ABIN561564
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, ICC
Validations
- (1)
- (3)
Cat. No.
ABIN2856549
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7156320
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (3)
Cat. No.
ABIN517271
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6741924
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6739033
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IHC (p)
Validations
- (1)
Cat. No.
ABIN2879401
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN632148
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (p), IF (cc), ICC, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN6943845
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN6943846
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN6978374
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN6977513
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN6976652
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN6979183
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our ITPK1 抗体
: "MLKL Requires the Inositol Phosphate Code to Execute Necroptosis." in: Molecular cell, Vol. 70, Issue 5, pp. 936-948.e7, (2019) (PubMed).: "Integration of cell cycle control with transcriptional regulation by the retinoblastoma protein." in: Current opinion in cell biology, Vol. 5, Issue 2, pp. 194-200, (1993) (PubMed).
: "The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity." in: Nature, Vol. 329, Issue 6140, pp. 642-5, (1987) (PubMed).
Aliases for ITPK1 抗体
inositol-tetrakisphosphate 1-kinase (ITPK1) 抗体inositol 1,3,4-triphosphate 5/6 kinase (Itpk1) 抗体
inositol-tetrakisphosphate 1-kinase L homeolog (itpk1.L) 抗体
inositol-tetrakisphosphate 1-kinase a (itpk1a) 抗体
inositol-tetrakisphosphate 1-kinase (Itpk1) 抗体
BC031182 抗体
ITRPK1 抗体
wu:fj15d08 抗体
zgc:56075 抗体
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