ITM2B 产品
(Integral Membrane Protein 2B (ITM2B))
Categories
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq, Oct 2009].
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Featured ITM2B Categories
Recommended ITM2B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IF, FACS
Validations
- (6)
Cat. No.
ABIN570955
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7156385
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IHC
Validations
- (2)
Cat. No.
ABIN7246220
Quantity
200 μL
Datasheet
Datasheet
Recommended ITM2B 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308241
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308239
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN7318631
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our ITM2B Products
: "The ITM2B (BRI2) gene is a target of BCL6 repression: Implications for lymphomas and neurodegenerative diseases." in: Biochimica et biophysica acta, Vol. 1852, Issue 5, pp. 742-8, (2015) (PubMed).: "Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy. ..." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 88, Issue 7, pp. 694-721, (2008) (PubMed).
Synonyms and alternative names related to ITM2B
integral membrane protein 2B (ITM2B), integral membrane protein 2B (Itm2b), integral membrane protein 2Ba (itm2ba), integral membrane protein 2B L homeolog (itm2b.L), integral membrane protein 2B (itm2b), integral membrane protein 2b (itm2b), integral membrane protein 2Bb (itm2bb), ABRI, AI256040, BRI, Bri, BRI2, Bri2, BRICD2B, Bricd2b, D14Sel6, E3-16, E25B, E25BMM, FBD, imBRI2, itm2b, ITM2B, itm2bl, MGC52745, MGC76131, wu:fb94b03, wu:fc05f02, zgc:55770, zgc:64142, zgc:85688Protein level used designations for ITM2B
- ABri/ADan amyloid peptide
- BRICHOS domain containing 2B
- immature BRI2
- transmembrane protein BRI
- Integral membrane protein 2B (E25B protein)
- integral membrane protein 2B
- putative transmembrane protein E3-16
- transmembrane protein E3-16
- BRICHOS-like protein
- integral membrane protein 2b
- fb94b03
- integral membrane protein 2B, like
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