Recombinant HEK-293 Cells IgG isotype control (His tag)
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- 抗原 See all IgG products
- IgG
- 抗体类型
- Recombinant Antibody
- 片段
- Fc fragment
- 适用
- 人
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宿主
- HEK-293 Cells
- 标记
- His tag
- 应用范围
- Isotype Control (IsoC)
- 产品特性
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27 kDa. The protein migrates as 34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- 亚型
- IgG
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
- 缓冲液
- 50 mM Tris, 100 mM Glycine, pH 7.5
- 储存条件
- -20 °C
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- 抗原
- IgG
- Abstract
- IgG 产品
- 物质类
- Antibody
- 背景
- Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
- 分子量
- 27 kDa
- UniProt
- P01857
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