This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.[provided by RefSeq, Oct 2010].
IRGM 抗体 by 适用
Find IRGM 抗体 for a variety of species such as anti-Human IRGM, anti-Mouse IRGM, anti-Rat IRGM. The species listed below are among those available. Click on a link to go to the corresponding products.
IRGM 抗体 by 应用范围
Find IRGM 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.
IRGM 抗体 by 抗体来源
Find IRGM 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
IRGM 抗体 by 抗原表位
Find IRGM 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
IRGM 抗体 by 克隆形成能力
Find available monoclonal or polyclonal IRGM 抗体. Click on a link to go to the corresponding products.
IRGM 抗体 by 克隆
Find IRGM 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
IRGM 抗体 by 标记
Find IRGM 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Fisher, Tremelling, Anderson, Gwilliam, Bumpstead, Prescott, Nimmo, Massey, Berzuini, Johnson, Barrett, Cummings, Drummond, Lees, Onnie, Hanson, Blaszczyk, Inouye, Ewels, Ravindrarajah, Keniry, Hunt et al.: "Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. ..." in: Nature genetics, Vol. 40, Issue 6, pp. 710-2, (2008) (PubMed).
Massey, Parkes: "Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease." in: Autophagy, Vol. 3, Issue 6, pp. 649-51, (2007) (PubMed).
Gozuacik, Kimchi: "Autophagy as a cell death and tumor suppressor mechanism." in: Oncogene, Vol. 23, Issue 16, pp. 2891-906, (2004) (PubMed).
Aliases for IRGM 抗体
immunity-related GTPase family M member 1 (Irgm1) 抗体 immunity-related GTPase M (Irgm) 抗体 immunity related GTPase M (IRGM) 抗体 immunity-related GTPase family M protein (LOC481473) 抗体 Ifi1 抗体 IFI1 抗体 Iigp3 抗体 Iipg3 抗体 Irgm 抗体 IRGM1 抗体 LRG-47 抗体 LRG47 抗体
