IRF6 抗体
(Interferon Regulatory Factor 6 (IRF6))
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011].
recommended
IRF6 适用: 人, 大鼠, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 2C10 unconjugated
recommended
recommended
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Popular IRF6 抗体
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Reactivity
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Validations
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Application
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Cat. No.
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Quantity
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Cat. No.
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Cat. No.
ABIN184730
Quantity
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Quantity
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Cat. No.
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Quantity
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Application
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Cat. No.
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Quantity
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Cat. No.
ABIN517233
Quantity
50 μg
Datasheet
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Bat, Cow, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Zebrafish (Danio rerio)
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WB, IHC, IHC (p)
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Cat. No.
ABIN1882373
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep, Zebrafish (Danio rerio)
Application
WB, IHC
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Cat. No.
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Quantity
50 μL
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Zebrafish (Danio rerio)
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ABIN6742300
Quantity
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Datasheet
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Reactivity
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Application
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Validations
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ABIN6742797
Quantity
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Datasheet
Datasheet
Latest Publications for our IRF6 抗体
: "IRF6 Regulates Alternative Activation by Suppressing PPARγ in Male Murine Macrophages." in: Endocrinology, Vol. 158, Issue 9, pp. 2837-2847, (2017) (PubMed).: "TGFβ3 regulates periderm removal through ΔNp63 in the developing palate." in: Journal of cellular physiology, Vol. 230, Issue 6, pp. 1212-25, (2015) (PubMed).
: "Smad4-Irf6 genetic interaction and TGF?-mediated IRF6 signaling cascade are crucial for palatal fusion in mice." in: Development (Cambridge, England), Vol. 140, Issue 6, pp. 1220-30, (2013) (PubMed).
: "Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 33, pp. 13710-5, (2011) (PubMed).
: "A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias." in: The Journal of clinical investigation, Vol. 120, Issue 5, pp. 1570-7, (2010) (PubMed).
: "Interferon regulatory factor 6 promotes cell cycle arrest and is regulated by the proteasome in a cell cycle-dependent manner." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2235-43, (2008) (PubMed).
: "Interferon regulatory factor 6 (IRF6) is associated with oral-facial cleft in individuals that originate in South America." in: American journal of medical genetics. Part A, Vol. 143A, Issue 17, pp. 2075-8, (2007) (PubMed).
: "Suggestive linkage to a neighboring region of IRF6 in a cleft lip and palate multiplex family." in: American journal of medical genetics. Part A, Vol. 143A, Issue 22, pp. 2716-21, (2007) (PubMed).
: "Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes. ..." in: Nature genetics, Vol. 32, Issue 2, pp. 285-9, (2002) (PubMed).
Aliases for IRF6 抗体
interferon regulatory factor 6 (IRF6) 抗体interferon regulatory factor 6 (irf6) 抗体
interferon regulatory factor 6 S homeolog (irf6.S) 抗体
interferon regulatory factor 6 (Irf6) 抗体
AI876454 抗体
DKFZp469E012 抗体
E230028I05Rik 抗体
IRF6 抗体
lps 抗体
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mirf6 抗体
ofc6 抗体
OFC6 抗体
pit 抗体
PIT 抗体
pps 抗体
PPS 抗体
PPS1 抗体
vws 抗体
VWS 抗体
VWS1 抗体
xIRF-6 抗体
zgc:63500 抗体
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