IRF4 产品
(Interferon Regulatory Factor 4 (IRF4))
Categories
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6\;14)(p25\;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010].
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Featured IRF4 Categories
IRF4 抗体
High quality antibodies with extensive validation data.
IRF4 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
IRF4 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IRF4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, RNAi
Validations
- (5)
Cat. No.
ABIN561526
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN561524
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6262655
Quantity
100 μL
Datasheet
Datasheet
Recommended IRF4 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956912
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648116
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6208784
Quantity
96 tests
Datasheet
Datasheet
Recommended IRF4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308086
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308088
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7412422
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our IRF4 Products
: "Size-Dependent Segregation Controls Macrophage Phagocytosis of Antibody-Opsonized Targets." in: Cell, Vol. 174, Issue 1, pp. 131-142.e13, (2018) (PubMed).: "Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma." in: eLife, Vol. 5, (2016) (PubMed).
: "Role of IRF4 in IFN-stimulated gene induction and maintenance of Kaposi sarcoma-associated herpesvirus latency in primary effusion lymphoma cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 3, pp. 1476-85, (2013) (PubMed).
: "A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation." in: PLoS genetics, Vol. 4, Issue 5, pp. e1000074, (2008) (PubMed).
: "NKL homeobox gene MSX1 acts like a tumor suppressor in NK-cell leukemia." in: Oncotarget, Vol. 8, Issue 40, pp. 66815-66832 (PubMed).
Synonyms and alternative names related to IRF4
interferon regulatory factor 4 (IRF4), interferon regulatory factor 4 (Irf4), interferon regulatory factor 4a (irf4a), Interferon regulatory factor 4 (irf4), PWWP domain-containing protein MUM1 (LOC612320), PWWP domain-containing protein MUM1 (LOC100068881), AI385587, IRF-4, IRF4, irf4, LSIRF, MUM1, NF-EM5, si:ch73-170d1.2, SpipProtein level used designations for IRF4
- lymphocyte-specific interferon regulatory factor
- multiple myeloma oncogene 1
- NF-EM5
- PU.1 interaction partner
- Sfpi1/PU.1 interaction partner
- transcriptional activator PIP
- interferon regulatory factor 4
- irf4
- Interferon regulatory factor 4
- PWWP domain-containing protein MUM1
- melanoma associated antigen (mutated) 1
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