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IRF1 产品

(Interferon Regulatory Factor 1 (IRF1))

Categories

IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion. [provided by RefSeq, Jul 2008].

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Featured IRF1 Categories

IRF1 抗体

High quality antibodies with extensive validation data.

IRF1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

IRF1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IRF1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7433789
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7263697
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (7)
  • (3)
Cat. No. ABIN561520
Quantity 100 μg
Datasheet Datasheet

Recommended IRF1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956908
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956909
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1138437
Quantity 96 tests
Datasheet Datasheet

Recommended IRF1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1308073
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123493
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308075
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our IRF1 Products

Dobson, Naing, Beug, Faye, Chabot, St-Jean, Walker, LaCasse, Stojdl, Korneluk, Holcik: "Oncolytic virus synergizes with Smac mimetic compounds to induce rhabdomyosarcoma cell death in a syngeneic murine model." in: Oncotarget, Vol. 8, Issue 2, pp. 3495-3508, (2018) (PubMed).

Larrea, Riezu-Boj, Aldabe, Guembe, Echeverria, Balasiddaiah, Gastaminza, Civeira, Sarobe, Prieto: "Dysregulation of interferon regulatory factors impairs the expression of immunostimulatory molecules in hepatitis C virus genotype 1-infected hepatocytes." in: Gut, Vol. 63, Issue 4, pp. 665-73, (2014) (PubMed).

Zhang, Leir, Harris: "Immune mediators regulate CFTR expression through a bifunctional airway-selective enhancer." in: Molecular and cellular biology, Vol. 33, Issue 15, pp. 2843-53, (2013) (PubMed).

Bartlett, Slater, Glanville, Haas, Caramori, Casolari, Clarke, Message, Aniscenko, Kebadze, Zhu, Mallia, Mizgerd, Belvisi, Papi, Kotenko, Johnston, Edwards: "Defining critical roles for NF-?B p65 and type I interferon in innate immunity to rhinovirus." in: EMBO molecular medicine, Vol. 4, Issue 12, pp. 1244-60, (2012) (PubMed).

Bego, Mercier, Cohen: "Virus-activated interferon regulatory factor 7 upregulates expression of the interferon-regulated BST2 gene independently of interferon signaling." in: Journal of virology, Vol. 86, Issue 7, pp. 3513-27, (2012) (PubMed).

Sun, Alkhoury, Wang, Foster, Radecke, Tam, Edwards, Facciotti, Armstrong, Knowlton, Newman, Passerini, Simon: "IRF-1 and miRNA126 modulate VCAM-1 expression in response to a high-fat meal." in: Circulation research, Vol. 111, Issue 8, pp. 1054-64, (2012) (PubMed).

Baumjohann, Okada, Ansel: "Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 5, pp. 2089-92, (2011) (PubMed).

Choi, Kageyama, Eto, Escobar, Johnston, Monticelli, Lao, Crotty: "ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6." in: Immunity, Vol. 34, Issue 6, pp. 932-46, (2011) (PubMed).

Fazilleau, McHeyzer-Williams, Rosen, McHeyzer-Williams: "The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding." in: Nature immunology, Vol. 10, Issue 4, pp. 375-84, (2009) (PubMed).

Nurieva, Chung, Martinez, Yang, Tanaka, Matskevitch, Wang, Dong: "Bcl6 mediates the development of T follicular helper cells." in: Science (New York, N.Y.), Vol. 325, Issue 5943, pp. 1001-5, (2009) (PubMed).

Synonyms and alternative names related to IRF1

interferon regulatory factor 1 (IRF1), interferon regulatory factor 1a (irf1a), interferon regulatory factor 1b (irf1b), interferon regulatory factor 1 (Irf1), AU020929, IRF-1, Irf-1, irf1, IRF1, irf11, MAR, zgc:103566, zgc:136945

Protein level used designations for IRF1

  • interferon regulatory factor 1
  • interferon regulatory factor 11
  • IRF-1
  • interferon responsive factor 1
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