IRAK3 产品
(Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
Categories
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010].
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Featured IRAK3 Categories
IRAK3 抗体
High quality antibodies with extensive validation data.
IRAK3 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
IRAK3 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IRAK3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, ICC, FACS
Validations
- (8)
Cat. No.
ABIN5542522
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (5)
Cat. No.
ABIN564872
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
Cat. No.
ABIN524643
Quantity
100 μg
Datasheet
Datasheet
Recommended IRAK3 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962181
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957196
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6218921
Quantity
96 tests
Datasheet
Datasheet
Recommended IRAK3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123628
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308063
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308065
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our IRAK3 Products
: "Transduction of Functionally Contrasting Signals by Two Mycobacterial PPE Proteins Downstream of TLR2 Receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 5, pp. 1776-87, (2016) (PubMed).: "Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M." in: Nature communications, Vol. 6, pp. 6062, (2015) (PubMed).
: "The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 2, pp. 1320-7, (2009) (PubMed).
: "IRAK-M is involved in the pathogenesis of early-onset persistent asthma. ..." in: American journal of human genetics, Vol. 80, Issue 6, pp. 1103-14, (2007) (PubMed).
: "Identification and characterization of murine IRAK-M." in: Biochemical and biophysical research communications, Vol. 293, Issue 5, pp. 1472-7, (2002) (PubMed).
: "IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex." in: Molecular cell, Vol. 5, Issue 3, pp. 513-22, (2000) (PubMed).
: "IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases." in: International immunology, Vol. 11, Issue 8, pp. 1357-62, (1999) (PubMed).
Synonyms and alternative names related to IRAK3
interleukin 1 receptor associated kinase 3 (IRAK3), interleukin-1 receptor-associated kinase 3 (irak3), interleukin-1 receptor-associated kinase 3 (Irak3), 4833428C18Rik, AI563835, ASRT5, IRAK-M, IRAK3, IRAKM, IrakM, si:dkey-150i15.2Protein level used designations for IRAK3
- interleukin-1 receptor-associated kinase 3
- interleukin-1 receptor-associated kinase 3-like
- IL-1 receptor-associated kinase M
- interleukin-1 receptor-associated kinase M
- IRAK-3
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