IQGAP1 产品
(IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))
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This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008].
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IQGAP1 抗体
High quality antibodies with extensive validation data.
IQGAP1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
IQGAP1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IQGAP1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN563819
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN7268020
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rabbit, Rat
Application
WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
- (1)
- (3)
Cat. No.
ABIN737796
Quantity
100 μL
Datasheet
Datasheet
Recommended IQGAP1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968056
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957205
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5656108
Quantity
96 tests
Datasheet
Datasheet
Recommended IQGAP1 蛋白
Latest Publications for our IQGAP1 Products
: "PAX6 downregulates miR-124 expression to promote cell migration during embryonic stem cell differentiation." in: Stem cells and development, Vol. 23, Issue 19, pp. 2297-310, (2014) (PubMed).: "Bile acids activate YAP to promote liver carcinogenesis." in: Cell reports, Vol. 5, Issue 4, pp. 1060-9, (2014) (PubMed).
: "Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis." in: Blood, Vol. 117, Issue 11, pp. 3151-62, (2011) (PubMed).
: "IQGAP1 integrates Ca2+/calmodulin and B-Raf signaling." in: The Journal of biological chemistry, Vol. 283, Issue 34, pp. 22972-82, (2008) (PubMed).
: "Insights into COPII coat nucleation from the structure of Sec23.Sar1 complexed with the active fragment of Sec31." in: Developmental cell, Vol. 13, Issue 5, pp. 635-45, (2007) (PubMed).
: "The zinc- and calcium-binding S100B interacts and co-localizes with IQGAP1 during dynamic rearrangement of cell membranes." in: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 49998-50007, (2002) (PubMed).
: "The activation of Rac1 by M3 muscarinic acetylcholine receptors involves the translocation of Rac1 and IQGAP1 to cell junctions and changes in the composition of protein complexes containing Rac1, IQGAP1, and actin." in: The Journal of biological chemistry, Vol. 277, Issue 36, pp. 33081-91, (2002) (PubMed).
: "Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1." in: Molecular and cellular biology, Vol. 20, Issue 2, pp. 697-701, (2000) (PubMed).
: "IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs." in: The EMBO journal, Vol. 15, Issue 12, pp. 2997-3005, (1996) (PubMed).
: "Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1." in: The Journal of biological chemistry, Vol. 271, Issue 38, pp. 23363-7, (1996) (PubMed).
Synonyms and alternative names related to IQGAP1
IQ motif containing GTPase activating protein 1 (IQGAP1), IQ motif containing GTPase activating protein 1 (Iqgap1), AA682088, D7Ertd237e, D7Ertd257e, HUMORFA01, mKIAA0051, p195, SAR1Protein level used designations for IQGAP1
- RasGAP-like with IQ motifs
- ras GTPase-activating-like protein IQGAP1
- Cdc42-Rac1 effector protein
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