IPO7 产品
(Importin 7 (IPO7))
Categories
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins. [provided by RefSeq, Jul 2008].
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Featured IPO7 Categories
Recommended IPO7 抗体
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Latest Publications for our IPO7 Products
: "Mutations in nuclear pore genes NUP93, NUP205 and XPO5 cause steroid-resistant nephrotic syndrome. ..." in: Nature genetics, Vol. 48, Issue 4, pp. 457-65, (2016) (PubMed).: "Androgen induces a switch from cytoplasmic retention to nuclear import of the androgen receptor." in: Molecular and cellular biology, Vol. 33, Issue 24, pp. 4766-78, (2013) (PubMed).
: "Intracellular mobility and nuclear trafficking of the stress-activated kinase JNK1 are impeded by hyperosmotic stress." in: Biochimica et biophysica acta, Vol. 1843, Issue 2, pp. 253-64, (2013) (PubMed).
: "Nuclear extracellular signal-regulated kinase 1 and 2 translocation is mediated by casein kinase 2 and accelerated by autophosphorylation." in: Molecular and cellular biology, Vol. 31, Issue 17, pp. 3515-30, (2011) (PubMed).
: "Nucleocytoplasmic shuttling of the zinc finger protein EZI Is mediated by importin-7-dependent nuclear import and CRM1-independent export mechanisms." in: The Journal of biological chemistry, Vol. 282, Issue 44, pp. 32327-37, (2007) (PubMed).
: "A novel class of RanGTP binding proteins." in: The Journal of cell biology, Vol. 138, Issue 1, pp. 65-80, (1997) (PubMed).
Synonyms and alternative names related to IPO7
importin 7 (ipo7), importin 7 S homeolog (ipo7.S), importin 7 (IPO7), importin-7 (CpipJ_CPIJ002096), importin-7 (PTRG_08544), karyopherin (SJAG_03693), importin-7 (NAEGRDRAFT_71372), importin-7 (VDBG_01971), importin-7 (MGYG_08162), importin-7 (Tsp_01943), importin-7 (Tsp_01946), importin 7 (Ipo7), A330055O14Rik, C330016G14, fb33d09, imp7, Imp7, ranbp7, RANBP7, Ranbp7, wu:fb33d09, zgc:66425, zgc:76878Protein level used designations for IPO7
- importin-7
- RAN binding protein 7
- importin 7
- RAN-binding protein 7
- ran-binding protein 7
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