Trichostatin A
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- 应用范围
- Inhibition (Inh)
- 原理
- HDAC inhibitor
- 产品特性
- Potent and selective histone deacetylase (HDAC) inhibitor (Ki = 3.4 nM). Induces reversion of ras transformed cells to normal morphology. Induces dedifferentiation of primordial germ cells into embryonic germ cells. Cell permeable and active in vivo.
- 纯度
- >98 %
- Chemical Name
- (2E,4E,6R)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
- Formula
- C17H22N2O3
- Permeability
- Cell-permeable
- Solubility
- Soluble in DMSO (up to 15 mg/ml), or in Ethanol (up to 3 mg/ml).
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- 限制
- 仅限研究用
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- 状态
- Powder
- 储存条件
- -20 °C
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- 背景
- TSA,Apoptosis inducer,Epigenetics,Cell cycle,Protein deacetylase,Stem cells,Cell death,Cancer,Infectious disease,Posttranslational modification,Chromatin
- 分子量
- 302.38
- CAS-编号
- 58880-19-6
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