Triacetylresveratrol
Quick Overview for Triacetylresveratrol (ABIN7233301)
应用范围
Chemical Name
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原理
- SIRT activator, prodrug
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产品特性
- A resveratrol prodrug. One method for increasing the half-life of resveratrol in vivo is acetylation of the phenolic OH groups. Deacetylation takes place in vivo or in intact cells via the action of intracellular esterases releasing active resveratrol. CWR22Rv1 cells when exposed to triacetyl resveratrol showed a G1S block concomitant with increased p53 and p21 expression. In MCF-7 cells it induced both ERK and p38 phosphorylation.
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纯度
- >98 %
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Formula
- C20H28O6
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Solubility
- Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 8 mg/ml).
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Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
Anacardic AcidInh 16611-84-0 2-Hydroxy-6-pentadecylbenzoic acid
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
ResveratrolAct 501-36-0 3,4',5-Trihydroxy-trans-stilbene
5-AzacytidineInh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
NicotinamideInh 98-92-0 Pyridine-3-carboxylic acid amide
AS-8351Inh 796-42-9 2-Hydroxy-1-naphthylaldehyde isonicotinolyhydrazone
UNC-0379Inh 1620401-82-2 6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)-pentyl)quinazolin-4-amine
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限制
- 仅限研究用
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状态
- Powder
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储存条件
- -20 °C
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背景
- 3,5,4'-Tri-O-acetylresveratrol,NFkappaB,Epigenetics,Apoptosis inducer,Hedgehog,PI3K,Protein deacetylase,Antioxidant,Cell death,Immunology,Cancer,Diabetes,Ageing,Posttranslational modification,Inflammation,Chromatin
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分子量
- 364.4
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CAS-编号
- 42206-94-0
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