Triacetylresveratrol
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- 应用范围
- Activation (Act)
- 原理
- SIRT activator, prodrug
- 产品特性
- A resveratrol prodrug. One method for increasing the half-life of resveratrol in vivo is acetylation of the phenolic OH groups. Deacetylation takes place in vivo or in intact cells via the action of intracellular esterases releasing active resveratrol. CWR22Rv1 cells when exposed to triacetyl resveratrol showed a G1S block concomitant with increased p53 and p21 expression. In MCF-7 cells it induced both ERK and p38 phosphorylation.
- 纯度
- >98 %
- Chemical Name
- 5-[(1E)-2-[4-(Acetyloxy)phenyl]ethenyl]-1,3-benzenediol-1,3-diacetate
- Formula
- C20H28O6
- Solubility
- Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 8 mg/ml).
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Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
ResveratrolAct 501-36-0 3,4',5-Trihydroxy-trans-stilbene
PanobinostatInh 404950-80-7 (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide
HPA (Hexyl-4-pentynoic acid)Inh Cell-permeable 96017-59-3 2-(2-Propynyl)octanoic acid (racemic)
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
DaminozideInh 1596-84-5 1-(2,2-Dimethylhydrazide)butanedioic acid
Mithramycin AInh 18378-89-7
PiceatannolInh 10083-24-6 3,3',4,5'-Tetrahydroxy-trans-stilbene
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- 限制
- 仅限研究用
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- 状态
- Powder
- 储存条件
- -20 °C
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- 背景
- 3,5,4'-Tri-O-acetylresveratrol,NFkappaB,Epigenetics,Apoptosis inducer,Hedgehog,PI3K,Protein deacetylase,Antioxidant,Cell death,Immunology,Cancer,Diabetes,Ageing,Posttranslational modification,Inflammation,Chromatin
- 分子量
- 364.4
- CAS-编号
- 42206-94-0
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