-
- 应用范围
- Inhibition (Inh)
- 原理
- SIRT1 and 2 inhibitor
- 产品特性
- Activates p53 via inhibition of SIRT1 and SIRT2. Induces apoptosis in a variety of cancer cell lines including cutaneous T-cell lymphoma and melanoma among others. Induces cellular senescence in cultured rat primary astrocytes6 as well as other cell types.
- 纯度
- >98 %
- Chemical Name
- N-[(4-Acetamidophenyl)carbamothioyl]-4-tert-butylbenzamide
- Formula
- C20H23N3O2S
- Solubility
- Soluble in DMSO (up tp 10 mg/ml, warm)
-
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
ResveratrolAct 501-36-0 3,4',5-Trihydroxy-trans-stilbene
PanobinostatInh 404950-80-7 (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide
HPA (Hexyl-4-pentynoic acid)Inh Cell-permeable 96017-59-3 2-(2-Propynyl)octanoic acid (racemic)
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
DaminozideInh 1596-84-5 1-(2,2-Dimethylhydrazide)butanedioic acid
Mithramycin AInh 18378-89-7
PiceatannolInh 10083-24-6 3,3',4,5'-Tetrahydroxy-trans-stilbene
-
- 限制
- 仅限研究用
-
- 状态
- Powder
- 储存条件
- -20 °C
-
- 背景
- Posttranslational modification,Epigenetics,Chromatin,Cell cycle,Protein deacetylase,Transcription factor,Cancer,Senescence,p53
- 分子量
- 369.5
- CAS-编号
- 380315-80-0
-
You are here:
