-
- 应用范围
- Inhibition (Inh)
- 原理
- HAT inhibitor
- 产品特性
- Garcinol is a HAT (histone acetyltransferase) inhibitor (p300 IC50=7μM and PCAF IC50=5μM) both in vitro and in vivo. It potentiates TRAIL-induced apoptosis of cancer cells. Garcinol, independent of the cell type, induces both of the TRAIL receptors, death receptor 4 (DR4) and DR5. Garcinol neither induces the receptors of normal cells nor sensitizes them to TRAIL.
- 纯度
- >98 %
- Formula
- C38H50O6
- Solubility
- Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
-
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
ResveratrolAct 501-36-0 3,4',5-Trihydroxy-trans-stilbene
PanobinostatInh 404950-80-7 (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide
HPA (Hexyl-4-pentynoic acid)Inh Cell-permeable 96017-59-3 2-(2-Propynyl)octanoic acid (racemic)
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
DaminozideInh 1596-84-5 1-(2,2-Dimethylhydrazide)butanedioic acid
Mithramycin AInh 18378-89-7
PiceatannolInh 10083-24-6 3,3',4,5'-Tetrahydroxy-trans-stilbene
-
- 限制
- 仅限研究用
-
- 状态
- Powder
- 储存条件
- -20 °C
-
- 背景
- Epigenetics,Posttranslational modification,Acetyltransferase,Cell death,Stem cells,Apoptosis inducer,Chromatin
- 分子量
- 602.80
- CAS-编号
- 78824-30-3
-
You are here:
