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C-646

Inh Cell-permeable 328968-36-1 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzoic acid
产品编号 ABIN7233239
发货至: 中国
  • 应用范围
    Inhibition (Inh)
    原理
    HAT inhibitor
    产品特性
    Potent and selective inhibitor of the histone acetyl transferase p300/CBP (Ki=400 nM ). Induces apoptosis in prostate cancer cells. Enhances fear extinction memory and synaptic plasticity in mice. Promotes tau deacetylation reducing levels of pathogenic p-tau. Cell permeable.
    纯度
    >98 %
    Chemical Name
    4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzoic acid
    Formula
    C24H19N3O6
    Permeability
    Cell-permeable
    Solubility
    Soluble in DMSO (up to 10 mg/ml).
  • 限制
    仅限研究用
  • 状态
    Powder
    储存条件
    -20 °C
  • 背景
    Transcription,Epigenetics,Apoptosis inducer,Acetyltransferase,Cell death,Neuroscience,Neurodegeneration,Cancer,Posttranslational modification,Chromatin
    分子量
    445.4
    CAS-编号
    328968-36-1
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