Integrin beta 4 产品
(Integrin beta 4 (ITGB4))
Categories
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured Integrin beta 4 Categories
Integrin beta 4 抗体
High quality antibodies with extensive validation data.
Integrin beta 4 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Integrin beta 4 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Integrin beta 4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, FACS, ELISA
Validations
- (1)
- (6)
Cat. No.
ABIN1724805
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, FACS, ELISA
Validations
- (6)
Cat. No.
ABIN5611133
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF
Validations
- (4)
Cat. No.
ABIN7156486
Quantity
100 μg
Datasheet
Datasheet
Recommended Integrin beta 4 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956849
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Quantitative
Validations
Cat. No.
ABIN1055086
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Dog
Analytical Method
Quantitative
Validations
Cat. No.
ABIN1055087
Quantity
96 tests
Datasheet
Datasheet
Recommended Integrin beta 4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123472
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308213
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN6388181
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Integrin beta 4 Products
: "Clinical impact of different exosomes' protein expression in pancreatic ductal carcinoma patients treated with standard first line palliative chemotherapy." in: PLoS ONE, Vol. 14, Issue 5, pp. e0215990, (2019) (PubMed).: "Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction." in: Scientific reports, Vol. 8, Issue 1, pp. 9690, (2018) (PubMed).
: "Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells." in: Scientific reports, Vol. 8, Issue 1, pp. 10019, (2018) (PubMed).
: "Human Adenovirus Type 37 Uses αVβ1 and α3β1 Integrins for Infection of Human Corneal Cells." in: Journal of virology, Vol. 91, Issue 5, (2017) (PubMed).
: "P2X7R blockade prevents NLRP3 inflammasome activation and brain injury in a rat model of intracerebral hemorrhage: involvement of peroxynitrite." in: Journal of neuroinflammation, Vol. 12, pp. 190, (2016) (PubMed).
: "Tumour exosome integrins determine organotropic metastasis. ..." in: Nature, Vol. 527, Issue 7578, pp. 329-35, (2015) (PubMed).
: "Reconstruction of auto-tissue-engineered lamellar cornea by dynamic culture for transplantation: a rabbit model." in: PLoS ONE, Vol. 9, Issue 4, pp. e93012, (2014) (PubMed).
: "Integrin α6β4 identifies human distal lung epithelial progenitor cells with potential as a cell-based therapy for cystic fibrosis lung disease." in: PLoS ONE, Vol. 8, Issue 12, pp. e83624, (2014) (PubMed).
: "Galectin-1 promotes lung cancer tumor metastasis by potentiating integrin α6β4 and Notch1/Jagged2 signaling pathway." in: Carcinogenesis, Vol. 34, Issue 6, pp. 1370-81, (2013) (PubMed).
: "Downregulation of integrin β4 decreases the ability of airway epithelial cells to present antigens." in: PLoS ONE, Vol. 7, Issue 4, pp. e32060, (2012) (PubMed).
Synonyms and alternative names related to Integrin beta 4
integrin subunit beta 4 (ITGB4), integrin beta 4 (Itgb4), integrin subunit beta 4 (Itgb4), AA407042, C230078O20, CD104Protein level used designations for Integrin beta 4
- integrin beta 4
- integrin beta-4
- CD104 antigen
- GP150
- integrin beta-4 subunit
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