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INSIG1 抗体

(Insulin Induced Gene 1 (INSIG1))
Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jun 2009].
INSIG1 抗体  (AA 1-87) INSIG1 抗体  (AA 1-87) INSIG1 抗体 (AA 1-87) (ABIN7156348)

INSIG1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

INSIG1 抗体  (Internal Region) INSIG1 抗体  (Internal Region) INSIG1 抗体 (Internal Region) (ABIN6262599)

INSIG1 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

INSIG1 抗体  (AA 63-112) INSIG1 抗体  (AA 63-112) INSIG1 抗体 (AA 63-112) (ABIN6748581)

INSIG1 适用: 人, 小鼠, 大鼠, Cow, 山羊, 马, 兔, 犬, 豚鼠, Pig, 猴, Hamster, 非洲爪蟾, Bat, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

INSIG1 抗体 by 适用

Find INSIG1 抗体 for a variety of species such as anti-Human INSIG1, anti-Mouse INSIG1, anti-Rat INSIG1. The species listed below are among those available. Click on a link to go to the corresponding products.

INSIG1 抗体 by 应用范围

Find INSIG1 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

INSIG1 抗体 by 抗体来源

Find INSIG1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

INSIG1 抗体 by 抗原表位

Find INSIG1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

INSIG1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal INSIG1 抗体. Click on a link to go to the corresponding products.

INSIG1 抗体 by 克隆

Find INSIG1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

INSIG1 抗体 by 标记

Find INSIG1 抗体 with a specific conjugate such as FITC, APC, Biotin. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular INSIG1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7156348
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6262599
Quantity 100 μL
Datasheet Datasheet

Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6748581
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN652887
Quantity 400 μL
Datasheet Datasheet

Application WB, IHC
Validations
  • (3)
Cat. No. ABIN2778634
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Goat, Hamster, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep, Xenopus laevis
Application WB
Validations
  • (1)
Cat. No. ABIN6740654
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB
Validations
  • (1)
Cat. No. ABIN6740652
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7267887
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN635167
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (2)
Cat. No. ABIN2778638
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7156351
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7156350
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7156349
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
Cat. No. ABIN7115274
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, FACS, IHC (p)
Validations
Cat. No. ABIN1812154
Quantity 400 μL
Datasheet Datasheet

Latest Publications for our INSIG1 抗体

Yu, Zhao, Lai, Chu, Hao, Feng, Zhang, Liu, Cheng, Li, Shen, Min: "LncRNA as ceRNAs may be involved in lactation process." in: Oncotarget, Vol. 8, Issue 58, pp. 98014-98028, (2017) (PubMed).

Segatto, Di Giovanni, Marino, Pallottini: "Analysis of the protein network of cholesterol homeostasis in different brain regions: an age and sex dependent perspective." in: Journal of cellular physiology, Vol. 228, Issue 7, pp. 1561-7, (2013) (PubMed).

Segatto, Trapani, Lecis, Pallottini: "Regulation of cholesterol biosynthetic pathway in different regions of the rat central nervous system." in: Acta physiologica (Oxford, England), Vol. 206, Issue 1, pp. 62-71, (2012) (PubMed).

Trapani, Segatto, Simeoni, Balducci, Dhawan, Parmar, Prasad, Saso, Incerpi, Pallottini: "Short- and long-term regulation of 3-hydroxy 3-methylglutaryl coenzyme A reductase by a 4-methylcoumarin." in: Biochimie, Vol. 93, Issue 7, pp. 1165-71, (2011) (PubMed).

De Marinis, Martini, Trentalance, Pallottini: "Sex differences in hepatic regulation of cholesterol homeostasis." in: The Journal of endocrinology, Vol. 198, Issue 3, pp. 635-43, (2008) (PubMed).

Roth, Looser, Kaufmann, Blättler, Rencurel, Huang, Moore, Meyer: "Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression." in: Molecular pharmacology, Vol. 73, Issue 4, pp. 1282-9, (2008) (PubMed).

Gong, Lee, Lee, Goldstein, Brown, Ye: "Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake." in: Cell metabolism, Vol. 3, Issue 1, pp. 15-24, (2006) (PubMed).

Engelking, Liang, Hammer, Takaishi, Kuriyama, Evers, Li, Horton, Goldstein, Brown: "Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins." in: The Journal of clinical investigation, Vol. 115, Issue 9, pp. 2489-98, (2005) (PubMed).

Aliases for INSIG1 抗体

insulin induced gene 1 (INSIG1) 抗体
insulin induced gene 1 (insig1) 抗体
insulin induced gene 1 L homeolog (insig1.L) 抗体
insulin induced gene 1 (Insig1) 抗体
1810013C12Rik 抗体
cl-6 抗体
CL-6 抗体
cl6 抗体
CL6 抗体
fb55a03 抗体
fi35b10 抗体
Insig-1 抗体
INSIG-1 抗体
wu:fb55a03 抗体
wu:fi35b10 抗体
zgc:55439 抗体
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