Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 产品
(Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
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This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010].
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Featured Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 Categories
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 抗体
High quality antibodies with extensive validation data.
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (9)
Cat. No.
ABIN7440890
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (2)
- (5)
Cat. No.
ABIN2855261
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (1)
- (5)
Cat. No.
ABIN3043876
Quantity
100 μg
Datasheet
Datasheet
Recommended Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967582
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956723
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956724
Quantity
96 tests
Datasheet
Datasheet
Recommended Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123422
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7396604
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7413295
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 Products
: "Glucocorticoids can induce BIM to trigger apoptosis in the absence of BAX and BAK1." in: Cell death & disease, Vol. 11, Issue 6, pp. 442, (2021) (PubMed).: "Restoration of miR-193a expression is tumor-suppressive in MYC amplified Group 3 medulloblastoma." in: Acta neuropathologica communications, Vol. 8, Issue 1, pp. 70, (2020) (PubMed).
: "Infection with flaviviruses requires BCLXL for cell survival." in: PLoS pathogens, Vol. 14, Issue 9, pp. e1007299, (2019) (PubMed).
: "The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells." in: Scientific reports, Vol. 9, Issue 1, pp. 16717, (2019) (PubMed).
: "Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer." in: Oncotarget, Vol. 7, Issue 41, pp. 67071-67086, (2018) (PubMed).
: "Novel-smoothened inhibitors for therapeutic targeting of naïve and drug-resistant hedgehog pathway-driven cancers." in: Acta pharmacologica Sinica, (2018) (PubMed).
: "The BCL-2 pro-survival protein A1 is dispensable for T cell homeostasis on viral infection." in: Cell death and differentiation, Vol. 24, Issue 3, pp. 523-533, (2018) (PubMed).
: "Requirement of GSK-3 for PUMA induction upon loss of pro-survival PI3K signaling." in: Cell death & disease, Vol. 9, Issue 5, pp. 470, (2018) (PubMed).
: "Precision Targeting of BFL-1/A1 and an ATM Co-dependency in Human Cancer." in: Cell reports, Vol. 24, Issue 13, pp. 3393-3403.e5, (2018) (PubMed).
: "JNK Promotes Epithelial Cell Anoikis by Transcriptional and Post-translational Regulation of BH3-Only Proteins." in: Cell reports, Vol. 21, Issue 7, pp. 1910-1921, (2018) (PubMed).
Synonyms and alternative names related to Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
MCL1, BCL2 family apoptosis regulator (MCL1), myeloid cell leukemia sequence 1 (Mcl1), MCL1, BCL2 family apoptosis regulator (Mcl1), MCL1, BCL2 family apoptosis regulator a (mcl1a), MCL1, BCL2 family apoptosis regulator b (mcl1b), small nucleolar RNA, H/ACA box 63 (SNORA63), AW556805, bcl2-L-3, BCL2L3, E3, E3-2, EAT, elF-4AII, fb72f02, Mcl-1, mcl-1, MCL1-ES, mcl1/EAT, MCL1L, MCL1S, RNE3, RNU107, SNORA63A, TM, wu:fb70a08, wu:fb72f02, zfMcl-1a, zfMLP1, zgc:109763, zgc:109835Protein level used designations for Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
- bcl-2-like protein 3
- bcl-2-related protein EAT/mcl1
- induced myeloid leukemia cell differentiation protein Mcl-1
- myeloid cell leukemia ES
- induced myeloid leukemia cell differentiation protein Mcl-1 homolog
- myeloid cell leukemia protein 1
- fb70a08
- BCL2 family apoptosis regulator
- LOW QUALITY PROTEIN: induced myeloid leukemia cell differentiation protein Mcl-1
- myeloid cell leukemia sequence 1 (BCL2-related)
- RNA, U107 small nucleolar
- RNA, small nucleolar E3
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