Importin 9 产品
(Importin 9 (IPO9))
Categories
Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of H2B histone (By similarity), RPS7 and RPL18A. Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. May also import H2A, H3, H4 histones (By similarity), RPL4 and RPL6.
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Featured Importin 9 Categories
Importin 9 抗体
High quality antibodies with extensive validation data.
Importin 9 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Importin 9 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7140094
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN6242408
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, ICC
Validations
- (2)
Cat. No.
ABIN185045
Quantity
100 μg
Datasheet
Datasheet
Recommended Importin 9 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6205253
Quantity
96 tests
Datasheet
Datasheet
Recommended Importin 9 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7422577
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094942
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3134611
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Importin 9 Products
: "Nuclear actin modulates cell motility via transcriptional regulation of adhesive and cytoskeletal genes." in: Scientific reports, Vol. 6, pp. 33893, (2016) (PubMed).: "Beta-like importins mediate the nuclear translocation of mitogen-activated protein kinases." in: Molecular and cellular biology, Vol. 34, Issue 2, pp. 259-70, (2013) (PubMed).
: "Active maintenance of nuclear actin by importin 9 supports transcription." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 9, pp. E544-52, (2012) (PubMed).
: "A novel nuclear protein, Twa1, and Muskelin comprise a complex with RanBPM." in: Gene, Vol. 303, pp. 47-54, (2003) (PubMed).
: "Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM." in: The Journal of biological chemistry, Vol. 277, Issue 39, pp. 36216-22, (2002) (PubMed).
: "Full-sized RanBPM cDNA encodes a protein possessing a long stretch of proline and glutamine within the N-terminal region, comprising a large protein complex." in: Gene, Vol. 272, Issue 1-2, pp. 25-33, (2001) (PubMed).
Synonyms and alternative names related to Importin 9
importin 9 (IPO9), importin 9 (Ipo9), importin 9 (ipo9), importin 9 L homeolog (ipo9.L), importin 9 (cnrP), RAN binding protein 9 (Ranbp9), RAN binding protein 9 L homeolog (ranbp9.L), RAN binding protein 9 (RANBP9), RAN binding protein 9 (ranbp9), 0710008K06Rik, AI845704, bpm-l, bpm90, C78347, cb457, DDBDRAFT_0205722, DDBDRAFT_0229883, DDB_0205722, DDB_0229883, Imp9, IPO9, MGC81741, mKIAA1192, Ranbp9, RanBP9, ranbp9, ranbp9-a, ranbp9-b, ranbp9b, RanBPM, RGD1561940, wu:fc23d12, zgc:66429, zgc:158650Protein level used designations for Importin 9
- importin-9
- ran-binding protein 9
- ranBP9
- Ran binding protein 9
- imp9a
- imp9b
- importin-9a
- importin-9b
- importin 9
- importin-9-like
- LOW QUALITY PROTEIN: ran-binding protein 9
- ran-binding protein M
- RAN binding protein 9 b
- Ran-binding protein M
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