Importin 4 产品
(Importin 4 (IPO4))
Categories
Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.
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Featured Importin 4 Categories
Importin 4 抗体
High quality antibodies with extensive validation data.
Importin 4 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Importin 4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN7267857
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7237258
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IF
Validations
- (3)
Cat. No.
ABIN7258502
Quantity
200 μL
Datasheet
Datasheet
Recommended Importin 4 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6211750
Quantity
96 tests
Datasheet
Datasheet
Recommended Importin 4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123414
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7421347
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3093101
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to Importin 4
importin 4 (IPO4), importin 4 (Ipo4), 8430408O15Rik, AA409693, Imp4, Imp4a, RanBP4Protein level used designations for Importin 4
- importin 4
- imp4b
- importin-4
- importin-4b
- ran-binding protein 4
- ranBP4
- imp4
- importin 4a
- importin-4a
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