IL4 Receptor 产品
(Interleukin 4 Receptor (IL4R))
Categories
This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012].
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Featured IL4 Receptor Categories
IL4 Receptor 抗体
High quality antibodies with extensive validation data.
IL4 Receptor ELISA试剂盒
Reliable ELISA kits for a wide range of species.
IL4 Receptor 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IL4 Receptor 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7434557
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7443335
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, FACS, ICC, IF (p), IHC (p)
Validations
- (2)
- (3)
Cat. No.
ABIN740565
Quantity
100 μL
Datasheet
Datasheet
Recommended IL4 Receptor ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (7)
- (1)
Cat. No.
ABIN6957153
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Pig
Analytical Method
Validations
Cat. No.
ABIN1138699
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380459
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended IL4 Receptor 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274993
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274989
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274992
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our IL4 Receptor Products
: "Neutrophil Extracellular Traps Reprogram IL-4/GM-CSF-Induced Monocyte Differentiation to Anti-inflammatory Macrophages." in: Frontiers in immunology, Vol. 8, pp. 523, (2017) (PubMed).: "Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue." in: Acta neuropathologica communications, Vol. 4, Issue 1, pp. 100, (2016) (PubMed).
: "Mast cells boost myeloid-derived suppressor cell activity and contribute to the development of tumor-favoring microenvironment." in: Cancer immunology research, Vol. 3, Issue 1, pp. 85-95, (2015) (PubMed).
: "PAR-2, IL-4R, TGF-? and TNF-? in bronchoalveolar lavage distinguishes extrinsic allergic alveolitis from sarcoidosis." in: Experimental and therapeutic medicine, Vol. 8, Issue 2, pp. 533-538, (2014) (PubMed).
: "Absence of a role for interleukin-13 in inflammatory bowel disease." in: European journal of immunology, Vol. 44, Issue 2, pp. 370-85, (2014) (PubMed).
: "IL-4 and IL-13 differentially regulate TLR-induced eosinophil-basophil differentiation of cord blood CD34+ progenitor cells." in: PLoS ONE, Vol. 9, Issue 6, pp. e100734, (2014) (PubMed).
: "Role of interleukin 4 and its receptor in clinical presentation of chronic extrinsic allergic alveolitis: a pilot study." in: Multidisciplinary respiratory medicine, Vol. 8, Issue 1, pp. 35, (2013) (PubMed).
: "Biomarkers of fibroproliferative healing in fibrosing idiopathic interstitial pneumonias." in: The open respiratory medicine journal, Vol. 6, pp. 160-4, (2013) (PubMed).
: "Construction and application of elastin like polypeptide containing IL-4 receptor targeting peptide." in: PLoS ONE, Vol. 8, Issue 12, pp. e81891, (2013) (PubMed).
: "Platelet ITAM signaling is critical for vascular integrity in inflammation." in: The Journal of clinical investigation, Vol. 123, Issue 2, pp. 908-16, (2013) (PubMed).
Synonyms and alternative names related to IL4 Receptor
interleukin 4 receptor (IL4R), interleukin 4 receptor, tandem duplicate 1 (il4r.1), interleukin 4 receptor (Il4r), interleukin 4 receptor, alpha (Il4ra), CD124, il-4ra, IL-4RA, IL4, IL4R, Il4r, IL4RA, Il4ra, zgc:113063Protein level used designations for IL4 Receptor
- interleukin 4 receptor alpha chain
- interleukin-4 receptor alpha chain
- interleukin-4 receptor subunit alpha
- interleukin 4 receptor
- IL-4RA-like protein 1
- il-4alpha
- interleukin 4 receptor alpha
- soluble IL-4 receptor alpha
- interleukin-4 receptor subunit alpha-like
- IL-4 receptor subunit alpha
- IL4R nirs variant 1
- IL-4R subunit alpha
- IL-4R-alpha
- IL-4RA
- interleukin 4 receptor, alpha
- interleukin 4 tv3
- interleukin 4 tv5
- interleukin-4 receptor alpha-chain
- IL-4 receptor alpha chain
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