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IL18RAP 产品

(Interleukin 18 Receptor Accessory Protein (IL18RAP))

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The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18. [provided by RefSeq, Jul 2008].

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Featured IL18RAP Categories

IL18RAP 抗体

High quality antibodies with extensive validation data.

IL18RAP ELISA试剂盒

Reliable ELISA kits for a wide range of species.

IL18RAP 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IL18RAP 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (3)
Cat. No. ABIN522252
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, FACS, IP
Validations
  • (1)
  • (2)
Cat. No. ABIN748058
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7156833
Quantity 100 μL
Datasheet Datasheet

Recommended IL18RAP ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957074
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN625250
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730108
Quantity 96 tests
Datasheet Datasheet

Recommended IL18RAP 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7274972
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274975
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274970
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our IL18RAP Products

Kobori, Hamasaki, Kitaura, Yamazaki, Nishinaka, Niwa, Nakao, Wake, Mori, Yoshino, Nishibori, Takahashi: "Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis." in: Frontiers in immunology, Vol. 9, pp. 334, (2019) (PubMed).

Kuwahara-Otani, Maeda, Kobayashi, Minato, Tanaka, Yamanishi, Hata, Li, Hayakawa, Noguchi, Okamura, Yagi: "Interleukin-18 and its receptor are expressed in gonadotropin-releasing hormone neurons of mouse and rat forebrain." in: Neuroscience letters, Vol. 650, pp. 33-37, (2018) (PubMed).

Spallanzani, Torres, Avila, Ziblat, Iraolagoitia, Rossi, Domaica, Fuertes, Rabinovich, Zwirner: "Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 5, pp. 2141-8, (2015) (PubMed).

Freeman, Meyer, Slifka: "Anti-inflammatory cytokines directly inhibit innate but not adaptive CD8+ T cell functions." in: Journal of virology, Vol. 88, Issue 13, pp. 7474-84, (2014) (PubMed).

Valente, Yoshida, Izadpanah, Delafontaine, Siebenlist, Chandrasekar: "Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatin." in: Cellular signalling, Vol. 25, Issue 6, pp. 1447-56, (2013) (PubMed).

Salani, Ciaramella, Bizzoni, Assogna, Caltagirone, Spalletta, Bossù: "Increased expression of interleukin-18 receptor in blood cells of subjects with mild cognitive impairment and Alzheimer's disease." in: Cytokine, Vol. 61, Issue 2, pp. 360-3, (2013) (PubMed).

Takei, Hoshino, Matsunaga, Sakazaki, Sawada, Oda, Takenaka, Imaoka, Kinoshita, Honda, Ida, Fukuda, Aizawa: "Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis." in: Arthritis research & therapy, Vol. 13, Issue 2, pp. R52, (2011) (PubMed).

Koskinen, Einarsdottir, Dukes, Heap, Dubois, Korponay-Szabo, Kaukinen, Kurppa, Ziberna, Vatta, Not, Ventura, Sistonen, Adány, Pocsai, Széles, Mäki, Kere, Wijmenga, van Heel, Saavalainen: "Association study of the IL18RAP locus in three European populations with coeliac disease." in: Human molecular genetics, Vol. 18, Issue 6, pp. 1148-55, (2009) (PubMed).

Badot, Galant, Nzeusseu Toukap, Theate, Maudoux, Van den Eynde, Durez, Houssiau, Lauwerys: "Gene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis." in: Arthritis research & therapy, Vol. 11, Issue 2, pp. R57, (2009) (PubMed).

de Jager, Vastert, Beekman, Wulffraat, Kuis, Coffer, Prakken: "Defective phosphorylation of interleukin-18 receptor beta causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis." in: Arthritis and rheumatism, Vol. 60, Issue 9, pp. 2782-93, (2009) (PubMed).

Synonyms and alternative names related to IL18RAP

interleukin 18 receptor accessory protein (IL18RAP), interleukin 18 receptor accessory protein (Il18rap), ACPL, CD218b, CDw218b, IL18RAP, IL18RB

Protein level used designations for IL18RAP

  • interleukin 18 receptor accessory protein
  • IL-18 receptor beta
  • interleukin-18 receptor accessory protein-like
  • CD218 antigen-like family member B
  • IL-18 receptor accessory protein
  • IL-18R-beta
  • IL-18RAcP
  • IL-18Rbeta
  • IL-1R-7
  • IL-1R7
  • IL-1RAcPL
  • interleukin-1 receptor 7
  • interleukin-18 receptor accessory protein
  • interleukin-18 receptor beta
  • AcPL accessory protein-like)
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