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IL12RB2 抗体

(Interleukin 12 Receptor, beta 2 (IL12RB2))
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. [provided by RefSeq, Apr 2012].
IL12RB2 抗体  (AA 301-400) IL12RB2 抗体  (AA 301-400) IL12RB2 抗体 (AA 301-400) (ABIN747878)

IL12RB2 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

IL12RB2 抗体 IL12RB2 抗体 IL12RB2 抗体 (ABIN7239068)

IL12RB2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

IL12RB2 抗体  (AA 756-783) IL12RB2 抗体  (AA 756-783) IL12RB2 抗体 (AA 756-783) (ABIN1904911)

IL12RB2 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated

IL12RB2 抗体 by 适用

Find IL12RB2 抗体 for a variety of species such as anti-Human IL12RB2, anti-Mouse IL12RB2, anti-Rat IL12RB2. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find IL12RB2 抗体 validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find IL12RB2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

IL12RB2 抗体 by 抗原表位

Find IL12RB2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

IL12RB2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal IL12RB2 抗体. Click on a link to go to the corresponding products.

IL12RB2 抗体 by 克隆

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IL12RB2 抗体 by 标记

Find IL12RB2 抗体 with a specific conjugate such as Biotin, FITC, APC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular IL12RB2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (5)
Cat. No. ABIN747878
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7239068
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, FACS, IHC (p)
Validations
  • (2)
Cat. No. ABIN1904911
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN517103
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN517104
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p), EIA
Validations
  • (3)
Cat. No. ABIN952881
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7433117
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7437797
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7156777
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN517102
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN6257608
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN2854423
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN1859337
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN4904030
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7156780
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our IL12RB2 抗体

Cunningham, Cardwell, Guan, Teixeiro, Daniels: "POSH Regulates CD4+ T Cell Differentiation and Survival." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 196, Issue 10, pp. 4003-13, (2016) (PubMed).

Nguyen, Frye, Zbesko, Stepanovic, Hayes, Urzua, Serrano, Beach, Doyle: "Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue." in: Acta neuropathologica communications, Vol. 4, Issue 1, pp. 100, (2016) (PubMed).

Filková, Vernerová, Hulejová, Prajzlerová, Veigl, Pavelka, Vencovský, Šenolt: "Pro-inflammatory effects of interleukin-35 in rheumatoid arthritis." in: Cytokine, Vol. 73, Issue 1, pp. 36-43, (2015) (PubMed).

Freeman, Meyer, Slifka: "Anti-inflammatory cytokines directly inhibit innate but not adaptive CD8+ T cell functions." in: Journal of virology, Vol. 88, Issue 13, pp. 7474-84, (2014) (PubMed).

Liao, Lin, Wang, Li, Leonard: "Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages." in: Nature immunology, Vol. 12, Issue 6, pp. 551-9, (2011) (PubMed).

Smeltz, Chen, Ehrhardt, Shevach: "Role of IFN-gamma in Th1 differentiation: IFN-gamma regulates IL-18R alpha expression by preventing the negative effects of IL-4 and by inducing/maintaining IL-12 receptor beta 2 expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 12, pp. 6165-72, (2002) (PubMed).

Chakir, Camilucci, Filion, Webb: "Differentiation of murine NK cells into distinct subsets based on variable expression of the IL-12R beta 2 subunit." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 9, pp. 4985-93, (2000) (PubMed).

Wu, Wang, Gadina, OShea, Presky, Magram: "IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 11, pp. 6221-8, (2000) (PubMed).

Lúdvíksson, Ehrhardt, Strober: "Role of IL-12 in intrathymic negative selection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 8, pp. 4349-59, (1999) (PubMed).

Wang, Wilkinson, Podlaski, Wu, Stern, Presky, Magram: "Characterization of mouse interleukin-12 p40 homodimer binding to the interleukin-12 receptor subunits." in: European journal of immunology, Vol. 29, Issue 6, pp. 2007-13, (1999) (PubMed).

Aliases for IL12RB2 抗体

interleukin 12 receptor subunit beta 2 (IL12RB2) 抗体
interleukin 12 receptor, beta 2 (Il12rb2) 抗体
interleukin 12 receptor subunit beta 2 (Il12rb2) 抗体
A930027I18Rik 抗体
Ifnm 抗体
IL-12RB2 抗体
IL12RB2 抗体
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