IL12RB2 抗体
(Interleukin 12 Receptor, beta 2 (IL12RB2))
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. [provided by RefSeq, Apr 2012].
recommended
IL12RB2 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
recommended
IL12RB2 抗体 by 适用
Find IL12RB2 抗体 for a variety of species such as anti-Human IL12RB2, anti-Mouse IL12RB2, anti-Rat IL12RB2. The species listed below are among those available. Click on a link to go to the corresponding products.
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Find IL12RB2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
IL12RB2 抗体 by 克隆形成能力
Find available monoclonal or polyclonal IL12RB2 抗体. Click on a link to go to the corresponding products.
IL12RB2 抗体 by 克隆
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IL12RB2 抗体 by 标记
Find IL12RB2 抗体 with a specific conjugate such as Biotin, FITC, APC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular IL12RB2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (5)
Cat. No.
ABIN747878
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN517103
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN517104
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, FACS, IHC (p)
Validations
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Cat. No.
ABIN1904911
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p), EIA
Validations
- (3)
Cat. No.
ABIN952881
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (1)
Cat. No.
ABIN7433117
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IP, ICC
Validations
- (1)
Cat. No.
ABIN7437797
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
ELISA, IF
Validations
- (1)
Cat. No.
ABIN7156777
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB
Validations
- (1)
Cat. No.
ABIN517102
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN6257608
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, ICC
Validations
- (2)
Cat. No.
ABIN1859337
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB
Validations
- (2)
Cat. No.
ABIN4904030
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
Cat. No.
ABIN7156780
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
Cat. No.
ABIN6389637
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our IL12RB2 抗体
: "POSH Regulates CD4+ T Cell Differentiation and Survival." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 196, Issue 10, pp. 4003-13, (2016) (PubMed).: "Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue." in: Acta neuropathologica communications, Vol. 4, Issue 1, pp. 100, (2016) (PubMed).
: "Pro-inflammatory effects of interleukin-35 in rheumatoid arthritis." in: Cytokine, Vol. 73, Issue 1, pp. 36-43, (2015) (PubMed).
: "Anti-inflammatory cytokines directly inhibit innate but not adaptive CD8+ T cell functions." in: Journal of virology, Vol. 88, Issue 13, pp. 7474-84, (2014) (PubMed).
: "Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages." in: Nature immunology, Vol. 12, Issue 6, pp. 551-9, (2011) (PubMed).
: "Role of IFN-gamma in Th1 differentiation: IFN-gamma regulates IL-18R alpha expression by preventing the negative effects of IL-4 and by inducing/maintaining IL-12 receptor beta 2 expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 12, pp. 6165-72, (2002) (PubMed).
: "Differentiation of murine NK cells into distinct subsets based on variable expression of the IL-12R beta 2 subunit." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 9, pp. 4985-93, (2000) (PubMed).
: "IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 11, pp. 6221-8, (2000) (PubMed).
: "Role of IL-12 in intrathymic negative selection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 8, pp. 4349-59, (1999) (PubMed).
: "Characterization of mouse interleukin-12 p40 homodimer binding to the interleukin-12 receptor subunits." in: European journal of immunology, Vol. 29, Issue 6, pp. 2007-13, (1999) (PubMed).
Aliases for IL12RB2 抗体
interleukin 12 receptor subunit beta 2 (IL12RB2) 抗体interleukin 12 receptor, beta 2 (Il12rb2) 抗体
interleukin 12 receptor subunit beta 2 (Il12rb2) 抗体
A930027I18Rik 抗体
Ifnm 抗体
IL-12RB2 抗体
IL12RB2 抗体
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