IL-6 Receptor 产品
(Interleukin 6 Receptor (IL6R))
Categories
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011].
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Featured IL-6 Receptor Categories
IL-6 Receptor 抗体
High quality antibodies with extensive validation data.
IL-6 Receptor ELISA试剂盒
Reliable ELISA kits for a wide range of species.
IL-6 Receptor 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IL-6 Receptor 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN7234279
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN3015522
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7434104
Quantity
100 μL
Datasheet
Datasheet
Recommended IL-6 Receptor ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (5)
Cat. No.
ABIN6720572
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
Cat. No.
ABIN6730982
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957177
Quantity
96 tests
Datasheet
Datasheet
Recommended IL-6 Receptor 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN6964085
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7092702
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123612
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our IL-6 Receptor Products
: "Endothelial HuR deletion reduces the expression of proatherogenic molecules and attenuates atherosclerosis." in: International immunopharmacology, Vol. 65, pp. 248-255, (2018) (PubMed).: "The IL6R gene polymorphisms are associated with sIL-6R, IgE and lung function in Chinese patients with asthma." in: Gene, Vol. 585, Issue 1, pp. 51-7, (2016) (PubMed).
: "Effect of alcohol on diethylnitrosamine-induced hepatic toxicity: Critical role of ROS, lipid accumulation, and mitochondrial dysfunction." in: Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, (2015) (PubMed).
: "Interleukin-6 and interleukin-6 receptor expression, localization, and involvement in pain-sensing neuron activation in a mouse intervertebral disc injury model." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 33, Issue 10, pp. 1508-14, (2015) (PubMed).
: "Establishment of a novel cell-based assay for screening small molecule antagonists of human interleukin-6 receptor." in: Acta pharmacologica Sinica, Vol. 35, Issue 11, pp. 1453-62, (2014) (PubMed).
: "Alterations of IL-6, IL-6R and gp130 in early and late onset severe preeclampsia." in: Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy, (2013) (PubMed).
: "Monoclonal anti-interleukin-6 receptor antibody attenuates donor-specific antibody responses in a mouse model of allosensitization." in: Transplant immunology, Vol. 28, Issue 2-3, pp. 138-43, (2013) (PubMed).
: "Anti-inflammatory activity of methyl palmitate and ethyl palmitate in different experimental rat models." in: Toxicology and applied pharmacology, Vol. 264, Issue 1, pp. 84-93, (2012) (PubMed).
: "Tumor necrosis factor-alpha (TNF-α)-blockade-induced hepatic sarcoidosis in psoriatic arthritis (PsA): case report and review of the literature." in: Clinical rheumatology, Vol. 30, Issue 1, pp. 133-7, (2011) (PubMed).
: "Significance of autologous interleukin-6 production in the HA22T/VGH cell model of hepatocellular carcinoma." in: Annals of the New York Academy of Sciences, Vol. 1089, pp. 268-75, (2007) (PubMed).
Synonyms and alternative names related to IL-6 Receptor
interleukin 6 receptor (IL6R), interleukin 6 receptor (il6r), interleukin 6 receptor (Il6r), interleukin 6 receptor, alpha (Il6ra), CD126, gp80, IL-6R, IL-6R-1, il-6ra, IL-6RA, IL-6Ralpha, IL6Q, IL6R, Il6r, IL6R1, IL6RA, Il6ra, IL6RQProtein level used designations for IL-6 Receptor
- interleukin 6 receptor
- interleukin 6 receptor alpha
- interleukin-6 receptor subunit alpha
- CD126 antigen
- IL-6 receptor subunit alpha
- IL-6R 1
- membrane glycoprotein 80
- IL-6R subunit alpha
- IL-6R-alpha
- IL-6RA
- interleukin 6 receptor, alpha
- IL-6 receptor alpha chain
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