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IL-24 产品

(Interleukin 24 (IL24))

Categories

This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

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Featured IL-24 Categories

IL-24 抗体

High quality antibodies with extensive validation data.

IL-24 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

IL-24 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IL-24 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7427543
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
Cat. No. ABIN6242397
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN2856609
Quantity 100 μL
Datasheet Datasheet

Recommended IL-24 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6957113
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6963587
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6963537
Quantity 96 tests
Datasheet Datasheet

Recommended IL-24 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (3)
Cat. No. ABIN6239770
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307794
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307790
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our IL-24 Products

Grilli, Bengalli, Longhin, Capasso, Proverbio, Forcato, Bicciato, Gualtieri, Battaglia, Camatini: "Transcriptional profiling of human bronchial epithelial cell BEAS-2B exposed to diesel and biomass ultrafine particles." in: BMC genomics, Vol. 19, Issue 1, pp. 302, (2019) (PubMed).

Mo, Liu, Bao, Li: "Effects of melanoma differentiation associated gene-7 (MDA-7/IL-24) on apoptosis of liver cancer cells via regulating the expression of B-cell lymphoma-2." in: Oncology letters, Vol. 18, Issue 1, pp. 29-34, (2019) (PubMed).

Chen, Zhou, Xiao, Huang, Zhang, Gu, Tang: "Inhibition of ALDH2 protects PC12 cells against formaldehyde-induced cytotoxicity: involving the protection of hydrogen sulphide." in: Clinical and experimental pharmacology & physiology, Vol. 44, Issue 5, pp. 595-601, (2017) (PubMed).

Sagara, Karasawa, Igarashi, Otsuka, Sugiura, Kodama, Yamashita, Narita, Kato: "Controlled Secretion of the Anticancer Protein MDA-7 from Engineered Mesenchymal Stem Cells." in: Biological & pharmaceutical bulletin, Vol. 40, Issue 1, pp. 113-117, (2017) (PubMed).

Liu, Chen, Wu, Wang, Feng, Li, Zhou, Wang, Wu, Liu, Liang: "Enhanced tumor growth inhibition by mesenchymal stem cells derived from iPSCs with targeted integration of interleukin24 into rDNA loci." in: Oncotarget, Vol. 8, Issue 25, pp. 40791-40803, (2017) (PubMed).

Liang, Yang, Gu, Zhang: "A conditionally replicating adenovirus expressing IL-24 acts synergistically with temozolomide to enhance apoptosis in melanoma cells in vitro." in: Oncology letters, Vol. 13, Issue 6, pp. 4185-4189, (2017) (PubMed).

Liu, Asanoma, Takao, Tsukimori, Uchi, Furue, Kato, Wake: "Aryl hydrocarbon receptor SNP -130 C/T associates with dioxins susceptibility through regulating its receptor activity and downstream effectors including interleukin 24." in: Toxicology letters, Vol. 232, Issue 2, pp. 384-92, (2015) (PubMed).

Presti, DOrazio, Labra, La Ferla, Mezzasalma, Bizzaro, Giardina, Michelotti, Tursi, Vassallo, Di Gennaro: "Evaluation of the probiotic properties of new Lactobacillus and Bifidobacterium strains and their in vitro effect." in: Applied microbiology and biotechnology, Vol. 99, Issue 13, pp. 5613-26, (2015) (PubMed).

Shefler, Pasmanik-Chor, Kidron, Mekori, Hershko: "T cell-derived microvesicles induce mast cell production of IL-24: relevance to inflammatory skin diseases." in: The Journal of allergy and clinical immunology, Vol. 133, Issue 1, pp. 217-24.e1-3, (2014) (PubMed).

Anuradha, George, Hanna, Kumaran, Chandrasekaran, Nutman, Babu: "Expansion of parasite-specific CD4+ and CD8+ T cells expressing IL-10 superfamily cytokine members and their regulation in human lymphatic filariasis." in: PLoS neglected tropical diseases, Vol. 8, Issue 4, pp. e2762, (2014) (PubMed).

Synonyms and alternative names related to IL-24

interleukin 24 (IL24), interleukin 24 (Il24), C49A, FISP, IL10B, IL24, Mda-7, MDA7, Mda7, MOB5, ST16, St16

Protein level used designations for IL-24

  • IL-4-induced secreted protein
  • interleukin-24
  • melanocyte-associated Mda-7
  • melanoma differentiation-associated gene 7 protein
  • suppression of tumorigenicity 16 (melanoma differentiation)
  • IL-24
  • th2-specific cytokine FISP
  • cytokine-like protein Mob-5
  • interleukin 24
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