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IL-21 产品

(Interleukin 21 (IL21))

Categories

This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].

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Featured IL-21 Categories

IL-21 抗体

High quality antibodies with extensive validation data.

IL-21 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

IL-21 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IL-21 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (7)
Cat. No. ABIN6142359
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, PLA
Validations
  • (5)
Cat. No. ABIN528381
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF (p), IHC (p)
Validations
  • (3)
  • (1)
Cat. No. ABIN748133
Quantity 100 μL
Datasheet Datasheet

Recommended IL-21 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6957095
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957096
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957097
Quantity 96 tests
Datasheet Datasheet

Recommended IL-21 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (3)
Cat. No. ABIN7274916
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN6964397
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7199412
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our IL-21 Products

Yamamoto, Kitawaki, Sugimoto, Fujita, Kawase, Takaori-Kondo, Kadowaki: "Anti-inflammatory modulation of human myeloid-derived dendritic cell subsets by lenalidomide." in: Immunology letters, Vol. 211, pp. 41-48, (2020) (PubMed).

Laestadius, Ingelman-Sundberg, Myrberg, Verme, Sundberg, Schweiger, Saghafian-Hedengren, Nilsson: "Altered proportions of circulating CXCR5+ helper T cells do not dampen influenza vaccine responses in children with rheumatic disease." in: Vaccine, Vol. 37, Issue 28, pp. 3685-3693, (2020) (PubMed).

Yang, Zhang, Xu, Wu, Zhao, Zhao: "Quercetin attenuates collagen-induced arthritis by restoration of Th17/Treg balance and activation of Heme Oxygenase 1-mediated anti-inflammatory effect." in: International immunopharmacology, Vol. 54, pp. 153-162, (2018) (PubMed).

Li, Jin, Wang, Li, Liu, Chang, Wang, Liu: "Live attenuated Salmonella displaying HIV-1 10E8 epitope on fimbriae: systemic and mucosal immune responses in BALB/c mice by mucosal administration." in: Scientific reports, Vol. 6, pp. 29556, (2018) (PubMed).

Zhou, Tong, Guan, Li, Feng, Zhou, Zhang: "Circulating follicular helper T cells presented distinctively different responses toward bacterial antigens in primary biliary cholangitis." in: International immunopharmacology, Vol. 51, pp. 76-81, (2018) (PubMed).

You, Zhang, Cui, Zhu, Lv, Tang, Sun: "Th9 cells promote antitumor immunity via IL-9 and IL-21 and demonstrate atypical cytokine expression in breast cancer." in: International immunopharmacology, Vol. 52, pp. 163-167, (2018) (PubMed).

Verstappen, Kroese, Meiners, Corneth, Huitema, Haacke, van der Vegt, Arends, Vissink, Bootsma, Abdulahad: "B Cell Depletion Therapy Normalizes Circulating Follicular Th Cells in Primary Sjögren Syndrome." in: The Journal of rheumatology, Vol. 44, Issue 1, pp. 49-58, (2017) (PubMed).

Shen, Yang, Yang, Wang, Cui, Zhou, Liu, Pan, Liu, Zhang, Zhang, Xie, Liu: "Hepatitis B virus persistence in mice reveals IL-21 and IL-33 as regulators of viral clearance." in: Nature communications, Vol. 8, Issue 1, pp. 2119, (2017) (PubMed).

Ma, Sun, Zhai, Yu, Wang, Li, Ding: "Effect of follicular helper T cells on the pathogenesis of asthma." in: Experimental and therapeutic medicine, Vol. 14, Issue 2, pp. 967-972, (2017) (PubMed).

Gong, Zhu, Pang, Ai, Gong, La, Ding: "Increased levels of CCR7(lo)PD-1(hi) CXCR5+ CD4+ T cells, and associated factors Bcl-6, CXCR5, IL-21 and IL-6 contribute to repeated implantation failure." in: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5931-5941, (2017) (PubMed).

Synonyms and alternative names related to IL-21

interleukin 21 (IL21), interleukin 21 (Il21), IL-21, Za11

Protein level used designations for IL-21

  • interleukin-21
  • interleukin-21 isoform
  • IL-21
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