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IL-19 产品

(Interleukin 19 (IL19))

Categories

The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008].

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Featured IL-19 Categories

IL-19 抗体

High quality antibodies with extensive validation data.

IL-19 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

IL-19 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IL-19 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7428044
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, ELISA
Validations
  • (4)
Cat. No. ABIN7239077
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7428212
Quantity 100 μL
Datasheet Datasheet

Recommended IL-19 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (5)
Cat. No. ABIN6730960
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967912
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957076
Quantity 96 tests
Datasheet Datasheet

Recommended IL-19 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274986
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123565
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307732
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our IL-19 Products

Bao, Alexander, Shi, Mohan, Chan: "Interleukin-4 up-regulation of epidermal interleukin-19 expression in keratinocytes involves the binding of signal transducer and activator of transcription 6 (Stat6) to the imperfect Stat6 sites." in: Immunology, Vol. 143, Issue 4, pp. 601-8, (2014) (PubMed).

Cooley, Chauhan, Donneyz, Marriott: "Astrocytes produce IL-19 in response to bacterial challenge and are sensitive to the immunosuppressive effects of this IL-10 family member." in: Glia, Vol. 62, Issue 5, pp. 818-28, (2014) (PubMed).

Amoroso, Falzoni, Adinolfi, Ferrari, Di Virgilio: "The P2X7 receptor is a key modulator of aerobic glycolysis." in: Cell death & disease, Vol. 3, pp. e370, (2012) (PubMed).

Uto-Konomi, Miyauchi, Ozaki, Motomura, Suzuki, Yoshimura, Suzuki, Cua, Kubo: "Dysregulation of suppressor of cytokine signaling 3 in keratinocytes causes skin inflammation mediated by interleukin-20 receptor-related cytokines." in: PLoS ONE, Vol. 7, Issue 7, pp. e40343, (2012) (PubMed).

Tohyama, Hanakawa, Shirakata, Dai, Yang, Hirakawa, Tokumaru, Okazaki, Sayama, Hashimoto: "IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression." in: European journal of immunology, Vol. 39, Issue 10, pp. 2779-88, (2009) (PubMed).

Tian, Sommerville, Cuneo, Kelemen, Autieri: "Expression and suppressive effects of interleukin-19 on vascular smooth muscle cell pathophysiology and development of intimal hyperplasia." in: The American journal of pathology, Vol. 173, Issue 3, pp. 901-9, (2008) (PubMed).

Huang, Wachi, Thai, Loukoianov, Tan, Forteza, Wu: "Potentiation of IL-19 expression in airway epithelia by IL-17A and IL-4/IL-13: important implications in asthma." in: The Journal of allergy and clinical immunology, Vol. 121, Issue 6, pp. 1415-21, 1421.e1-3, (2008) (PubMed).

Chang, Magracheva, Kozlov, Fong, Tobin, Kotenko, Wlodawer, Zdanov: "Crystal structure of interleukin-19 defines a new subfamily of helical cytokines." in: The Journal of biological chemistry, Vol. 278, Issue 5, pp. 3308-13, (2003) (PubMed).

Synonyms and alternative names related to IL-19

interleukin 19 (IL19), interleukin 19 (Il19), IL-10C, IL19, MDA1, NG.1, ZMDA1

Protein level used designations for IL-19

  • interleukin-19
  • melanoma differentiation associated protein-like protein
  • melanoma differentiation-associated protein-like protein
  • IL-19
  • interleukin 19
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