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IKK alpha 产品

(conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008].

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Featured IKK alpha Categories

IKK alpha 抗体

High quality antibodies with extensive validation data.

IKK alpha ELISA试剂盒

Reliable ELISA kits for a wide range of species.

IKK alpha 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IKK alpha 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (3)
  • (9)
Cat. No. ABIN3022825
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (6)
Cat. No. ABIN6256173
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (5)
Cat. No. ABIN560378
Quantity 100 μg
Datasheet Datasheet

Recommended IKK alpha ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955060
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6999499
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1137999
Quantity 96 tests
Datasheet Datasheet

Recommended IKK alpha 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349452
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5508965
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3093092
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our IKK alpha Products

He, Wang, Lu, Yang, Xue, Zhu, Zhang, Fan: "Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations." in: Oncogene, Vol. 40, Issue 2, pp. 355-368, (2021) (PubMed).

Liang, Ma, Zhong, Dhar, Liu, Xu, Koyama, Nishio, Karin, Karin, Mccubbin, Zhang, Hu, Yang, Chen, Ganguly, Lan, Karin, Kisseleva, Brenner: "NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice." in: Gastroenterology, Vol. 156, Issue 4, pp. 1156-1172.e6, (2019) (PubMed).

Page, Ortega, Alameda, Navarro, Paramio, Saiz-Pardo, Almeida, Hernández, Fernández-Aceñero, García-Fernández, Casanova: "IKKα Promotes the Progression and Metastasis of Non-Small Cell Lung Cancer Independently of its Subcellular Localization." in: Computational and structural biotechnology journal, Vol. 17, pp. 251-262, (2019) (PubMed).

Balkhi, Willette-Brown, Wittmann, Hu: "IKKα deficiency disrupts the development of marginal zone and follicular B cells." in: Genes and immunity, (2018) (PubMed).

Wang, Wang, Liu, Wang, Xu, Liu, Zhu, Chen, Situ, Lin: "Broadleaf Mahonia attenuates granulomatous lobular mastitis‑associated inflammation by inhibiting CCL‑5 expression in macrophages." in: International journal of molecular medicine, Vol. 41, Issue 1, pp. 340-352, (2018) (PubMed).

Diamanti, Gupta, Bennecke, De Oliveira, Ramakrishnan, Braczynski, Richter, Beli, Hu, Saleh, Mittelbronn, Dikic, Greten: "IKKα controls ATG16L1 degradation to prevent ER stress during inflammation." in: The Journal of experimental medicine, Vol. 214, Issue 2, pp. 423-437, (2017) (PubMed).

Zhu, Willette-Brown, Song, Lomada, Song, Xue, Gray, Zhao, Davis, Sun, Zhang, Wu, Zhan, Richie, Hu: "Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis." in: Cell host & microbe, Vol. 21, Issue 4, pp. 478-493.e7, (2017) (PubMed).

Schwartz, Bochkariov: "Novel chemiluminescent Western blot blocking and antibody incubation solution for enhanced antibody-antigen interaction and increased specificity." in: Electrophoresis, Vol. 38, Issue 20, pp. 2631-2637, (2017) (PubMed).

Todoric, Antonucci, Di Caro, Li, Wu, Lytle, Dhar, Banerjee, Fagman, Browne, Umemura, Valasek, Kessler, Tarin, Goggins, Reya, Diaz-Meco, Moscat, Karin: "Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas." in: Cancer cell, Vol. 32, Issue 6, pp. 824-839.e8, (2017) (PubMed).

Gao, Yang, Yuan, Huang, Xu, Mao, Yuan, Bi: "TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration." in: Oncogenesis, Vol. 6, Issue 9, pp. e383, (2017) (PubMed).

Synonyms and alternative names related to IKK alpha

conserved helix-loop-helix ubiquitous kinase S homeolog (chuk.S), conserved helix-loop-helix ubiquitous kinase (CHUK), conserved helix-loop-helix ubiquitous kinase (Chuk), conserved helix-loop-helix ubiquitous kinase (chuk), AI256658, CHUK, Chuk1, Fbx24, Fbxo24, IKBKA, ikk, IKK-alpha, ikk1, IKK1, ikka, IKKA, Ikka, ikkalpha, NFKBIKA, TCF16, zgc:56539

Protein level used designations for IKK alpha

  • IKK-A
  • IKK-alpha
  • NFKBIKA
  • i kappa-B kinase alpha
  • ikBKA
  • inhibitor of nuclear factor kappa-B kinase subunit alpha
  • nuclear factor NF-kappa-B inhibitor kinase alpha
  • SPFH domain-containing protein 1
  • conserved helix-loop-helix ubiquitous kinase
  • I-kappa-B kinase 1
  • I-kappa-B kinase-alpha
  • IKK-a kinase
  • IkB kinase alpha subunit
  • Nuclear factor NFkappaB inhibitor kinase alpha
  • TCF-16
  • transcription factor 16
  • I kappa B kinase 1
  • I-kappa-B kinase alpha
  • IKK alpha
  • IkappaB kinase alpha
  • ikappaB kinase
  • IkB kinase-a
  • IKK1
  • IKKa
  • pky
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