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IGF2BP2 产品

(Insulin-Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2))

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This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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Featured IGF2BP2 Categories

IGF2BP2 抗体

High quality antibodies with extensive validation data.

IGF2BP2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

IGF2BP2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IGF2BP2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Monkey
Application WB, IHC, IF, FACS, IHC (p)
Validations
  • (6)
Cat. No. ABIN1498821
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey
Application WB, IHC, IF, FACS, IHC (p)
Validations
  • (7)
Cat. No. ABIN1498822
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (5)
Cat. No. ABIN524080
Quantity 100 μg
Datasheet Datasheet

Recommended IGF2BP2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967648
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6974539
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951048
Quantity 96 tests
Datasheet Datasheet

Recommended IGF2BP2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123455
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307556
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307555
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our IGF2BP2 Products

Rivera Vargas, Boudoukha, Simon, Souidi, Cuvellier, Pinna, Polesskaya: "Post-transcriptional regulation of cyclins D1, D3 and G1 and proliferation of human cancer cells depend on IMP-3 nuclear localization." in: Oncogene, Vol. 33, Issue 22, pp. 2866-75, (2014) (PubMed).

Li, Zhang, Ramanujan, Ma, Kirsch, Glass: "Oncogenic NRAS, required for pathogenesis of embryonic rhabdomyosarcoma, relies upon the HMGA2-IGF2BP2 pathway." in: Cancer research, Vol. 73, Issue 10, pp. 3041-50, (2013) (PubMed).

Schaeffer, Hansen, Morris, LeBoeuf, Abrass: "RNA-binding protein IGF2BP2/IMP2 is required for laminin-?2 mRNA translation and is modulated by glucose concentration." in: American journal of physiology. Renal physiology, Vol. 303, Issue 1, pp. F75-82, (2012) (PubMed).

Boudoukha, Cuvellier, Polesskaya: "Role of the RNA-binding protein IMP-2 in muscle cell motility." in: Molecular and cellular biology, Vol. 30, Issue 24, pp. 5710-25, (2010) (PubMed).

Zeggini, Weedon, Lindgren, Frayling, Elliott, Lango, Timpson, Perry, Rayner, Freathy, Barrett, Shields, Morris, Ellard, Groves, Harries, Marchini, Owen, Knight, Cardon, Walker, Hitman, Morris, Doney et al.: "Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. ..." in: Science (New York, N.Y.), Vol. 316, Issue 5829, pp. 1336-41, (2007) (PubMed).

Synonyms and alternative names related to IGF2BP2

insulin like growth factor 2 mRNA binding protein 2 (IGF2BP2), insulin-like growth factor 2 mRNA binding protein 2 (Igf2bp2), C330012H03Rik, IMP-2, IMP2, Imp2, Neilsen, p62, RGD1305614, VICKZ2

Protein level used designations for IGF2BP2

  • IGF-II mRNA-binding protein 2
  • IGF2 mRNA-binding protein 2
  • VICKZ family member 2
  • hepatocellular carcinoma autoantigen p62
  • insulin-like growth factor 2 mRNA-binding protein 2
  • insulin-like growth factor 2, binding protein 2
  • IMP-2
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