IFNT3 蛋白
(Interferon tau-3 (IFNT3))
Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.
antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.
Recommended IFNT3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Synonyms and alternative names related to IFNT3
interferon tau-3 (IFNT3), IFNTProtein level used designations for IFNT3
- IFN-tau-3
- IFN-tau3
- TP-1
- antiluteolysin
- trophoblast antiluteolytic protein
- trophoblast protein 1
- trophoblastin
You are here:
