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IFITM3 产品

(Interferon-Induced Transmembrane Protein 3 (IFITM3))

Categories

The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. [provided by RefSeq, May 2012].

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Featured IFITM3 Categories

IFITM3 抗体

High quality antibodies with extensive validation data.

IFITM3 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

IFITM3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IFITM3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IP
Validations
  • (6)
Cat. No. ABIN523802
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN6142186
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, IHC (p)
Validations
  • (6)
  • (6)
Cat. No. ABIN387989
Quantity 400 μL
Datasheet Datasheet

Recommended IFITM3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5655616
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967765
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1138518
Quantity 96 tests
Datasheet Datasheet

Recommended IFITM3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1307445
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123503
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7196277
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our IFITM3 Products

Luo, Huang, Luo, Liao, Wang, Deng, Ma, Ma, Zhou: "Identification of genes underlying the enhancement of immunity by a formula of lentinan, pachymaran and tremelia polysaccharides in immunosuppressive mice." in: Scientific reports, Vol. 8, Issue 1, pp. 10082, (2018) (PubMed).

Savidis, Perreira, Portmann, Meraner, Guo, Green, Brass: "The IFITMs Inhibit Zika Virus Replication." in: Cell reports, Vol. 15, Issue 11, pp. 2323-30, (2017) (PubMed).

Mäkelä, Österlund, Westenius, Latvala, Diamond, Gale, Julkunen: "RIG-I Signaling Is Essential for Influenza B Virus-Induced Rapid Interferon Gene Expression." in: Journal of virology, Vol. 89, Issue 23, pp. 12014-25, (2015) (PubMed).

Zhang, Zhang, Zan, Du, Yang, Tien: "Human respiratory syncytial virus infection is inhibited by IFN-induced transmembrane proteins." in: The Journal of general virology, Vol. 96, Issue Pt 1, pp. 170-82, (2014) (PubMed).

John, Chin, Perreira, Feeley, Aker, Savidis, Smith, Elia, Everitt, Vora, Pertel, Elledge, Kellam, Brass: "The CD225 domain of IFITM3 is required for both IFITM protein association and inhibition of influenza A virus and dengue virus replication." in: Journal of virology, Vol. 87, Issue 14, pp. 7837-52, (2013) (PubMed).

Jia, Pan, Ding, Rong, Liu, Geng, Qiao, Liang: "The N-terminal region of IFITM3 modulates its antiviral activity by regulating IFITM3 cellular localization." in: Journal of virology, Vol. 86, Issue 24, pp. 13697-707, (2012) (PubMed).

Everitt, Clare, Pertel, John, Wash, Smith, Chin, Feeley, Sims, Adams, Wise, Kane, Goulding, Digard, Anttila, Baillie, Walsh, Hume, Palotie, Xue, Colonna, Tyler-Smith, Dunning, Gordon, Smyth, Openshaw et al.: "IFITM3 restricts the morbidity and mortality associated with influenza. ..." in: Nature, Vol. 484, Issue 7395, pp. 519-23, (2012) (PubMed).

Li, Peng, Tang, Wei, Kong, Yan, Huang, Li, Le, Li, Xie: "KLF4-mediated negative regulation of IFITM3 expression plays a critical role in colon cancer pathogenesis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 11, pp. 3558-68, (2011) (PubMed).

Yao, Dong, Zhu, Nelson, Liu, Lambiase, Li: "Identification of the IFITM3 gene as an inhibitor of hepatitis C viral translation in a stable STAT1 cell line." in: Journal of viral hepatitis, Vol. 18, Issue 10, pp. e523-9, (2011) (PubMed).

Feeley, Sims, John, Chin, Pertel, Chen, Gaiha, Ryan, Donis, Elledge, Brass: "IFITM3 inhibits influenza A virus infection by preventing cytosolic entry." in: PLoS pathogens, Vol. 7, Issue 10, pp. e1002337, (2011) (PubMed).

Synonyms and alternative names related to IFITM3

Interferon-induced transmembrane protein 3 (ifm3), interferon induced transmembrane protein 3 (Ifitm3), interferon induced transmembrane protein 3 (IFITM3), 1-8U, 1110004C05Rik, Cd225, Cdw217, DSPA2b, Fgls, IP15, mil-1, rat8

Protein level used designations for IFITM3

  • Interferon-induced transmembrane protein 3
  • dispanin subfamily A member 2b
  • fragilis protein
  • ifitm-like protein 1
  • interferon-induced transmembrane protein 3
  • interferon-inducible protein 15
  • interferon-inducible protein 1-8U
  • interferon-inducible protein variant 10
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