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IFIH1 产品

(Interferon Induced with Helicase C Domain 1 (IFIH1))

Categories

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents\; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. [provided by RefSeq, Jul 2012].

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Featured IFIH1 Categories

IFIH1 抗体

High quality antibodies with extensive validation data.

IFIH1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

IFIH1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IFIH1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN6142174
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6258879
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6262453
Quantity 100 μL
Datasheet Datasheet

Recommended IFIH1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967752
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956907
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6229146
Quantity 96 tests
Datasheet Datasheet

Recommended IFIH1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123492
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307422
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307420
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our IFIH1 Products

Szymura, Bernal, Wu, Zhang, Crawley, Voce, Campbell, Ranoa, Weichselbaum, Yamini: "DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-κB and sensitize to alkylating chemotherapy." in: BMC biology, Vol. 18, Issue 1, pp. 32, (2020) (PubMed).

Zhu, Duan, Wang, Cao, Liu: "TREM-1 activation modulates dsRNA induced antiviral immunity with specific enhancement of MAPK signaling and the RLRs and TLRs on macrophages." in: Experimental cell research, Vol. 345, Issue 1, pp. 70-81, (2016) (PubMed).

Cheng, Liao, Zhou, Peng, Chen, Yuan: "Amplified RLR signaling activation through an interferon-stimulated gene-endoplasmic reticulum stress-mitochondrial calcium uniporter protein loop." in: Scientific reports, Vol. 6, pp. 20158, (2016) (PubMed).

Miro, Laaref, Rofidal, Lagrafeuille, Hem, Thorel, Méchin, Mamchaoui, Mouly, Claustres, Tuffery-Giraud: "FUBP1: a new protagonist in splicing regulation of the DMD gene." in: Nucleic acids research, Vol. 43, Issue 4, pp. 2378-89, (2015) (PubMed).

Hua, Yuan, Li, Coursey, Pflugfelder, Li: "A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins." in: PLoS ONE, Vol. 10, Issue 6, pp. e0128039, (2015) (PubMed).

Choi, Lakamp-Hawley, Kolar, Yan, Borgstahl, Ouellette: "The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs." in: Biochimie, Vol. 115, pp. 17-27, (2015) (PubMed).

Mellett, Atzei, Bergin, Horgan, Floss, Wurst, Callanan, Moynagh: "Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions." in: Nature communications, Vol. 6, pp. 6669, (2015) (PubMed).

Su, Cheng, Chen, Chang, Tsai, Kung, Wang, Lin, Huang, Chang, Su, Chiang, Cheng, Lin, Lu: "Investigation of the caspase-dependent mitochondrial apoptotic pathway in mononuclear cells of patients with systemic lupus erythematosus." in: Journal of translational medicine, Vol. 12, Issue 1, pp. 303, (2014) (PubMed).

Labrador-Horrillo, Martinez, Selva-OCallaghan, Trallero-Araguas, Balada, Vilardell-Tarres, Juárez: "Anti-MDA5 antibodies in a large Mediterranean population of adults with dermatomyositis." in: Journal of immunology research, Vol. 2014, pp. 290797, (2014) (PubMed).

Tansley, Betteridge, Gunawardena, Jacques, Owens, Pilkington, Arnold, Yasin, Moraitis, Wedderburn, McHugh: "Anti-MDA5 autoantibodies in juvenile dermatomyositis identify a distinct clinical phenotype: a prospective cohort study." in: Arthritis research & therapy, Vol. 16, Issue 4, pp. R138, (2014) (PubMed).

Synonyms and alternative names related to IFIH1

interferon induced with helicase C domain 1 (IFIH1), interferon induced with helicase C domain 1 (Ifih1), 9130009C22Rik, Helicard, Hlcd, IDDM19, MDA-5, MDA5, RGD1560496, RLR-2

Protein level used designations for IFIH1

  • interferon-induced helicase C domain-containing protein 1
  • melanoma differentiation associated protein-5
  • melanoma differentiation-associated protein 5
  • CADM-140 autoantigen
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide
  • RIG-I-like receptor 2
  • RNA helicase-DEAD box protein 116
  • clinically amyopathic dermatomyositis autoantigen 140 kDa
  • helicard
  • helicase with 2 CARD domains
  • murabutide down-regulated protein
  • interferon induced with helicase C domain protein 1
  • melanoma differentiation associated protein 5
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