IDH2 抗体
(Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. [provided by RefSeq, Jul 2008].
recommended
IDH2 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
recommended
recommended
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Popular IDH2 抗体
Product
Reactivity
Application
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Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro), ICC
Validations
- (7)
Cat. No.
ABIN7441520
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, IF, ChIP
Validations
- (1)
- (5)
Cat. No.
ABIN6142146
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, FACS
Validations
- (6)
Cat. No.
ABIN7193379
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN561418
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (7)
Cat. No.
ABIN3043856
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IHC (p)
Validations
- (4)
Cat. No.
ABIN574283
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Saccharomyces cerevisiae, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
- (4)
Cat. No.
ABIN2783282
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
- (3)
Cat. No.
ABIN751558
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7157125
Quantity
100 μL
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Datasheet
Reactivity
Human, Mouse, Pig, Rat
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN571275
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN561417
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN516803
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF, ICC
Validations
- (2)
Cat. No.
ABIN6262445
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7157124
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6741027
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our IDH2 抗体
: "Isocitrate Dehydrogenase Mutations Confer Dasatinib Hypersensitivity and SRC Dependence in Intrahepatic Cholangiocarcinoma. ..." in: Cancer discovery, Vol. 6, Issue 7, pp. 727-39, (2016) (PubMed).: "Identification of proteins responsible for adriamycin resistance in breast cancer cells using proteomics analysis." in: Scientific reports, Vol. 5, pp. 9301, (2016) (PubMed).
: "Single muscle fiber proteomics reveals unexpected mitochondrial specialization." in: EMBO reports, Vol. 16, Issue 3, pp. 387-95, (2015) (PubMed).
: "Altered global methylation and hydroxymethylation status in vulvar lichen sclerosus: further support for epigenetic mechanisms." in: The British journal of dermatology, Vol. 170, Issue 3, pp. 687-93, (2014) (PubMed).
: "Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer. ..." in: Nature, Vol. 513, Issue 7516, pp. 110-4, (2014) (PubMed).
: "Elevated CO(2) levels cause mitochondrial dysfunction and impair cell proliferation." in: The Journal of biological chemistry, Vol. 286, Issue 43, pp. 37067-76, (2011) (PubMed).
: "Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value." in: Blood, Vol. 116, Issue 12, pp. 2122-6, (2010) (PubMed).
: "Silencing of mitochondrial NADP+-dependent isocitrate dehydrogenase by small interfering RNA enhances heat shock-induced apoptosis." in: Biochemical and biophysical research communications, Vol. 366, Issue 4, pp. 1012-8, (2008) (PubMed).
: "Expression patterns of members of the isocitrate dehydrogenase gene family in murine inner ear." in: Biotechnic & histochemistry : official publication of the Biological Stain Commission, Vol. 92, Issue 7, pp. 536-544 (PubMed).
Aliases for IDH2 抗体
isocitrate dehydrogenase subunit 2 (IDH2) 抗体isocitrate dehydrogenase (NADP(+)) 2, mitochondrial (IDH2) 抗体
isocitrate dehydrogenase 2 (NADP+), mitochondrial (Idh2) 抗体
isocitrate dehydrogenase (NADP(+)) 2, mitochondrial (Idh2) 抗体
isocitrate dehydrogenase 2 (NADP+), mitochondrial S homeolog (idh2.S) 抗体
isocitrate dehydrogenase 2 (NADP+), mitochondrial (idh2) 抗体
isocitrate dehydrogenase [NADP], mitochondrial (LOC100441867) 抗体
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E430004F23 抗体
F6P23.14 抗体
F6P23_14 抗体
ICD-M 抗体
IDH 抗体
Idh-2 抗体
IDH-II 抗体
idh2 抗体
IDH2 抗体
IDHM 抗体
IDP 抗体
IDPM 抗体
IDPm 抗体
isocitrate dehydrogenase II 抗体
isocitrate dehydrogenase subunit 2 抗体
mNADP-IDH 抗体
NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 2 抗体
wu:fb33c06 抗体
wu:fk31e05 抗体
wu:fq43b01 抗体
zgc:55485 抗体
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