Id2 产品
(Inhibitor of DNA Binding 2 (Id2))
Categories
The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Aug 2011].
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Featured Id2 Categories
Recommended Id2 抗体
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ABIN3021262
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Recommended Id2 蛋白
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Cat. No.
ABIN1098783
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ABIN1307351
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Latest Publications for our Id2 Products
: "Pharmacogenomic analysis of patient-derived tumor cells in gynecologic cancers." in: Genome biology, Vol. 20, Issue 1, pp. 253, (2019) (PubMed).: "Contribution of Polycomb group proteins to olfactory basal stem cell self-renewal in a novel c-KIT+ culture model and in vivo." in: Development (Cambridge, England), Vol. 143, Issue 23, pp. 4394-4404, (2016) (PubMed).
: "CHD7 interacts with BMP R-SMADs to epigenetically regulate cardiogenesis in mice." in: Human molecular genetics, Vol. 23, Issue 8, pp. 2145-56, (2014) (PubMed).
: "ID2: A negative transcription factor regulating oligodendroglia differentiation." in: Journal of neuroscience research, Vol. 90, Issue 5, pp. 925-32, (2012) (PubMed).
: "Myocardial Mycn is essential for mouse ventricular wall morphogenesis." in: Developmental biology, Vol. 373, Issue 1, pp. 53-63, (2012) (PubMed).
: "The transcriptional repressor ID2 can interact with the canonical clock components CLOCK and BMAL1 and mediate inhibitory effects on mPer1 expression." in: The Journal of biological chemistry, Vol. 285, Issue 50, pp. 38987-9000, (2010) (PubMed).
: "Coupling of cell growth control and apoptosis functions of Id proteins." in: Molecular and cellular biology, Vol. 18, Issue 4, pp. 2371-81, (1998) (PubMed).
: "Id helix-loop-helix proteins in cell growth and differentiation." in: Trends in cell biology, Vol. 8, Issue 2, pp. 58-65, (1998) (PubMed).
: "Expression of the Id family helix-loop-helix regulators during growth and development in the hematopoietic system." in: Blood, Vol. 89, Issue 9, pp. 3155-65, (1997) (PubMed).
: "Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors." in: The EMBO journal, Vol. 16, Issue 2, pp. 332-42, (1997) (PubMed).
Synonyms and alternative names related to Id2
inhibitor of DNA binding 2 (Id2), inhibitor of DNA binding 2, HLH protein (Id2), inhibitor of DNA binding 2 (ID2), inhibitor of DNA binding 2 L homeolog (id2.L), Ac2-300, AI255428, bHLHb26, C78922, GIG8, id2-A, ID2A, ID2H, Idb2, XId2Protein level used designations for Id2
- DNA-binding protein inhibitor ID-2
- inhibitor of differentiation 2
- Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
- DNA-binding protein inhibitor ID2
- cell growth-inhibiting gene 8
- class B basic helix-loop-helix protein 26
- helix-loop-helix protein ID2
- DNA-binding protein inhibitor ID-2-A
- Inhibitor of DNA binding 2-A
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