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HSPG 产品

(Heparan Sulphate Protoglycans (HSPG))
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008].

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Featured HSPG Categories

HSPG 抗体

High quality antibodies with extensive validation data.

HSPG ELISA试剂盒

Reliable ELISA kits for a wide range of species.

HSPG 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HSPG 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7432070
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Rat
Application WB, IHC, IHC (p), IP, ICC, IHC (fro)
Validations
  • (2)
Cat. No. ABIN625887
Quantity 50 μg
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Rat
Application WB, IHC, IHC (p), IP, ICC, IHC (fro)
Validations
  • (7)
Cat. No. ABIN335359
Quantity 0.1 mg
Datasheet Datasheet

Recommended HSPG ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (8)
  • (1)
Cat. No. ABIN6954521
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954522
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6963169
Quantity 96 tests
Datasheet Datasheet

Recommended HSPG 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7391033
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7391036
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3009814
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our HSPG Products

Dekker, Veerhoek, Koning, van Leeuwen, Elbers, van den Brom, Vonk, Boer: "Postoperative microcirculatory perfusion and endothelial glycocalyx shedding following cardiac surgery with cardiopulmonary bypass." in: Anaesthesia, Vol. 74, Issue 5, pp. 609-618, (2019) (PubMed).

Gao, Zhang, Wang, Liu, He, Liu, Wang, Feng, Yang, Wang, Meng, Yan: "The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis." in: Nature communications, Vol. 8, pp. 15279, (2018) (PubMed).

Alyoussef, Al-Gayyar: "Cytotoxic and partial hepatoprotective activity of sodium ascorbate against hepatocellular carcinoma through inhibition of sulfatase-2 in vivo and in vitro." in: Biomedicine & pharmacotherapy, Vol. 103, pp. 362-372, (2018) (PubMed).

Zhai, Wang, Zhang, Liang, Fu, Cui, Yang, Gong, Li, Yu, Xie, Yang, Yang, Gao: "Glioma targeting peptide modified apoferritin nanocage." in: Drug delivery, Vol. 25, Issue 1, pp. 1013-1024, (2018) (PubMed).

Nelson, Johansson, Tydén, Bodelsson: "Circulating syndecans during critical illness." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 125, Issue 5, pp. 468-475, (2017) (PubMed).

Arthur, McCall, Jolly, Kinsella, Kirk, Shelley: "Endothelial glycocalyx layer shedding following lung resection." in: Biomarkers in medicine, Vol. 10, Issue 10, pp. 1033-1038, (2016) (PubMed).

Martin, Schmitz, De Santis, Doemming, Haase, Hoeger, Heinbockel, Brandenburg, Marx, Schuerholz: "Peptide 19-2.5 inhibits heparan sulfate-triggered inflammation in murine cardiomyocytes stimulated with human sepsis serum." in: PLoS ONE, Vol. 10, Issue 5, pp. e0127584, (2016) (PubMed).

Jung, Fuernau, Muench, Desch, Eitel, Schuler, Adams, Figulla, Thiele: "Impairment of the endothelial glycocalyx in cardiogenic shock and its prognostic relevance." in: Shock (Augusta, Ga.), Vol. 43, Issue 5, pp. 450-5, (2015) (PubMed).

Tayel, Abd El Galil, Ebrahim, Ibrahim, El-Gayar, Al-Gayyar: "Suramin inhibits hepatic tissue damage in hepatocellular carcinoma through deactivation of heparanase enzyme." in: European journal of pharmacology, Vol. 728, pp. 151-60, (2014) (PubMed).

Al-ofi, Coffelt, Anumba: "Fibrinogen, an endogenous ligand of Toll-like receptor 4, activates monocytes in pre-eclamptic patients." in: Journal of reproductive immunology, Vol. 103, pp. 23-8, (2014) (PubMed).

Synonyms and alternative names related to HSPG

CD44 molecule (Indian blood group) (CD44), glypican 3 (GPC3), CD44 antigen (Cd44), CD44 molecule (Indian blood group) (Cd44), AU023126, AW121933, AW146109, CD44A, CDW44, CSPG8, ECMR-III, HCELL, HERMES, HUTCH-I, IN, LHR, Ly-24, MC56, MDU2, MDU3, METAA, MIC4, Pgp-1, Pgp1, RHAMM

Protein level used designations for HSPG

  • CD44 antigen
  • GP90 lymphocyte homing/adhesion receptor
  • Hermes antigen
  • cell surface glycoprotein CD44
  • chondroitin sulfate proteoglycan 8
  • epican
  • extracellular matrix receptor III
  • hematopoietic cell E- and L-selectin ligand
  • heparan sulfate proteoglycan
  • homing function and Indian blood group system
  • hyaluronate receptor
  • phagocytic glycoprotein 1
  • ECMR-III
  • HUTCH-I
  • PGP-I
  • hermes antigen
  • lymphocyte antigen 24
  • phagocytic glycoprotein I
  • Cell surface glycoprotein CD44 (hyaluronate binding protein)
  • PGP-1
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