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HSD11B1 抗体

(Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011].
HSD11B1 抗体  (AA 201-292) HSD11B1 抗体  (AA 201-292) HSD11B1 抗体 (AA 201-292) (ABIN750913)

HSD11B1 适用: 人, 小鼠, 大鼠, 马 ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

HSD11B1 抗体  (N-Term) HSD11B1 抗体  (N-Term) HSD11B1 抗体 (N-Term) (ABIN7218624)

HSD11B1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

HSD11B1 抗体  (N-Term) HSD11B1 抗体  (N-Term) HSD11B1 抗体 (N-Term) (ABIN2773867)

HSD11B1 适用: 人, 小鼠, 大鼠, 犬, 兔, 绵羊, Cow, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

HSD11B1 抗体 by Grade

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HSD11B1 抗体 by 适用

Find HSD11B1 抗体 for a variety of species such as anti-Human HSD11B1, anti-Mouse HSD11B1, anti-Rat HSD11B1. The species listed below are among those available. Click on a link to go to the corresponding products.

HSD11B1 抗体 by 应用范围

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HSD11B1 抗体 by 抗原表位

Find HSD11B1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

HSD11B1 抗体 by 克隆形成能力

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HSD11B1 抗体 by 克隆

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HSD11B1 抗体 by 标记

Find HSD11B1 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular HSD11B1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Horse, Human, Mouse, Rat
Application ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
  • (2)
  • (4)
Cat. No. ABIN750913
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (5)
Cat. No. ABIN7218624
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
Application WB, IHC
Validations
  • (2)
  • (5)
Cat. No. ABIN2773867
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
Cat. No. ABIN516704
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), ICC, IF, IHC (fro)
Validations
  • (1)
  • (3)
Cat. No. ABIN2855871
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7148610
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN516703
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN516702
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, ICC, IF
Validations
  • (2)
Cat. No. ABIN6257907
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN2450697
Quantity 1 each
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN768641
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN185329
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Sheep
Application WB, IHC, IHC (p), ICC, IHC (fro)
Validations
  • (1)
Cat. No. ABIN1903435
Quantity 50 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN1868430
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
Cat. No. ABIN6943729
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our HSD11B1 抗体

Oleinik, Kim, Roth, Selvam, Gooz, Johnson, Lemasters, Ogretmen: "Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress." in: Science advances, Vol. 5, Issue 9, pp. eaax1978, (2019) (PubMed).

Liu, Guo, Wang, Zhu, Li, Mi, Myatt, Sun: "Inhibition of Lysyl Oxidase by Cortisol Regeneration in Human Amnion: Implications for Rupture of Fetal Membranes." in: Endocrinology, Vol. 157, Issue 10, pp. 4055-4065, (2017) (PubMed).

Matsumura, Terao, Itami, Katayama: "Local cortisol activation is involved in EGF-induced immunosuppression." in: Dermato-endocrinology, Vol. 9, Issue 1, pp. e1412018, (2017) (PubMed).

Nakata, Umeda, Masuzaki, Sawai: "The expression of 11β-hydroxysteroid dehydrogenase type 1 is increased in experimental periodontitis in rats." in: BMC oral health, Vol. 16, Issue 1, pp. 108, (2016) (PubMed).

Xu, Zhao, Lin, Xiang, Wang, Ye, Huang: "Preeclampsia is associated with a deficiency of lipoxin A4, an endogenous anti-inflammatory mediator." in: Fertility and sterility, Vol. 102, Issue 1, pp. 282-290.e4, (2014) (PubMed).

Kuroda, Venkatakrishnan, Salker, Lucas, Shaheen, Kuroda, Blanks, Christian, Quenby, Brosens: "Induction of 11?-HSD 1 and activation of distinct mineralocorticoid receptor- and glucocorticoid receptor-dependent gene networks in decidualizing human endometrial stromal cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 2, pp. 192-202, (2013) (PubMed).

Lei, Chen, Georgiou, Sooranna, Khanjani, Brosens, Bennett, Johnson: "Progesterone acts via the nuclear glucocorticoid receptor to suppress IL-1?-induced COX-2 expression in human term myometrial cells." in: PLoS ONE, Vol. 7, Issue 11, pp. e50167, (2012) (PubMed).

Sinclair, Walker, Burdon, van Beek, Kema, Hughes, Murray, Nightingale, Stewart, Rauz, Tomlinson: "Cerebrospinal fluid corticosteroid levels and cortisol metabolism in patients with idiopathic intracranial hypertension: a link between 11beta-HSD1 and intracranial pressure regulation?" in: The Journal of clinical endocrinology and metabolism, Vol. 95, Issue 12, pp. 5348-56, (2010) (PubMed).

Paterson, Morton, Fievet, Kenyon, Holmes, Staels, Seckl, Mullins: "Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 18, pp. 7088-93, (2004) (PubMed).

Aliases for HSD11B1 抗体

hydroxysteroid 11-beta dehydrogenase 1 (HSD11B1) 抗体
hydroxysteroid (11-beta) dehydrogenase 1b (HSD11B1b) 抗体
hydroxysteroid (11-beta) dehydrogenase 1 L homeolog (hsd11b1.L) 抗体
hydroxysteroid 11-beta dehydrogenase 1 (Hsd11b1) 抗体
11-beta-HSD1 抗体
11-DH 抗体
CORTRD2 抗体
HDL 抗体
HSD11 抗体
hsd11 抗体
HSD11B 抗体
hsd11b 抗体
HSD11L 抗体
LRRGT00065 抗体
SDR26C1 抗体
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