HSD11B1 产品
(Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
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The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011].
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Featured HSD11B1 Categories
HSD11B1 抗体
High quality antibodies with extensive validation data.
HSD11B1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
HSD11B1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HSD11B1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Horse, Human, Mouse, Rat
Application
ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
- (2)
- (4)
Cat. No.
ABIN750913
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (5)
Cat. No.
ABIN7218624
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
Application
WB, IHC
Validations
- (2)
- (5)
Cat. No.
ABIN2773867
Quantity
100 μL
Datasheet
Datasheet
Recommended HSD11B1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956632
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6956634
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967494
Quantity
96 tests
Datasheet
Datasheet
Recommended HSD11B1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123384
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307101
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7396115
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our HSD11B1 Products
: "Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress." in: Science advances, Vol. 5, Issue 9, pp. eaax1978, (2019) (PubMed).: "Synthesis of the N-methyl Derivatives of 2-Aminothiazol-4(5H)-one and Their Interactions with 11βHSD1-Molecular Modeling and in Vitro Studies." in: Chemistry & biodiversity, Vol. 16, Issue 6, pp. e1900065, (2019) (PubMed).
: "A novel derivatives of thiazol-4(5H)-one and their activity in the inhibition of 11β-hydroxysteroid dehydrogenase type 1." in: Bioorganic chemistry, Vol. 79, pp. 115-121, (2019) (PubMed).
: "Inhibition of Lysyl Oxidase by Cortisol Regeneration in Human Amnion: Implications for Rupture of Fetal Membranes." in: Endocrinology, Vol. 157, Issue 10, pp. 4055-4065, (2017) (PubMed).
: "Local cortisol activation is involved in EGF-induced immunosuppression." in: Dermato-endocrinology, Vol. 9, Issue 1, pp. e1412018, (2017) (PubMed).
: "The expression of 11β-hydroxysteroid dehydrogenase type 1 is increased in experimental periodontitis in rats." in: BMC oral health, Vol. 16, Issue 1, pp. 108, (2016) (PubMed).
: "Piper sarmentosum Effects on 11β-Hydroxysteroid Dehydrogenase Type 1 Enzyme in Serum and Bone in Rat Model of Glucocorticoid-Induced Osteoporosis." in: Molecules (Basel, Switzerland), Vol. 21, Issue 11, (2016) (PubMed).
: "Anti-Inflammatory Property of Plantago major Leaf Extract Reduces the Inflammatory Reaction in Experimental Acetaminophen-Induced Liver Injury." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 347861, (2015) (PubMed).
: "A calcium-deficient diet in rat dams during gestation and nursing affects hepatic 11?-hydroxysteroid dehydrogenase-1 expression in the offspring." in: PLoS ONE, Vol. 9, Issue 1, pp. e84125, (2014) (PubMed).
: "Preeclampsia is associated with a deficiency of lipoxin A4, an endogenous anti-inflammatory mediator." in: Fertility and sterility, Vol. 102, Issue 1, pp. 282-290.e4, (2014) (PubMed).
Synonyms and alternative names related to HSD11B1
hydroxysteroid 11-beta dehydrogenase 1 (HSD11B1), hydroxysteroid (11-beta) dehydrogenase 1b (HSD11B1b), hydroxysteroid (11-beta) dehydrogenase 1 L homeolog (hsd11b1.L), hydroxysteroid 11-beta dehydrogenase 1 (Hsd11b1), 11-beta-HSD1, 11-DH, CORTRD2, HDL, HSD11, hsd11, HSD11B, hsd11b, HSD11L, LRRGT00065, SDR26C1Protein level used designations for HSD11B1
- 11-beta-hydroxysteroid dehydrogenase 1
- hydroxysteroid 11-beta dehydrogenase 1
- hydroxysteroid (11-beta) dehydrogenase 1
- corticosteroid 11-beta-dehydrogenase isozyme 1
- short chain dehydrogenase/reductase family 26C, member 1
- 11-DH
- 11-beta-HSD1
- 11-beta-hydroxysteroid dehydrogenase type 1
- 11-beta hydroxysteroid dehydrogenase
- 11 beta-hydroxysteroid dehydrogenase type 1
- 7-alpha-HCD
- 7-alpha-hydroxycholesterol dehydrogenase
- 11beta-HSD-1
- 11beta-HSD1A
- 11beta-hydroxysteroid dehydrogenase type 1
- Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A)
- cortocosteroid 11-beta dehydrogenase
- hydroxysteroid dehydrogenase, 11 beta type 1
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