HRPT2 抗体
(Parafibromin (CDC73))
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009].
recommended
CDC73 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB23239 unconjugated
recommended
recommended
HRPT2 抗体 by 应用范围
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HRPT2 抗体 by 克隆形成能力
Find available monoclonal or polyclonal HRPT2 抗体. Click on a link to go to the corresponding products.
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Popular HRPT2 抗体
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Reactivity
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Validations
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Datasheet
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Application
WB, IF, FACS, IHC (p)
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Quantity
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Cat. No.
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Cat. No.
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Quantity
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Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
ELISA, IHC (p), IHC (fro)
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
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Datasheet
Reactivity
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Quantity
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Datasheet
Reactivity
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Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN5008344
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN901334
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN901326
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN901328
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN901330
Quantity
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Datasheet
Datasheet
Latest Publications for our HRPT2 抗体
: "Histone H3R17me2a mark recruits human RNA polymerase-associated factor 1 complex to activate transcription." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 15, pp. 5675-80, (2012) (PubMed).: "The tumor suppressor, parafibromin, mediates histone H3 K9 methylation for cyclin D1 repression." in: Nucleic acids research, Vol. 38, Issue 2, pp. 382-90, (2010) (PubMed).
: "The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3'-end processing of animal histone mRNAs." in: Nucleic acids research, Vol. 38, Issue 21, pp. 7637-50, (2010) (PubMed).
: "The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 3, pp. 755-60, (2009) (PubMed).
: "Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice." in: Molecular and cellular biology, Vol. 28, Issue 9, pp. 2930-40, (2008) (PubMed).
: "The parafibromin tumor suppressor protein inhibits cell proliferation by repression of the c-myc proto-oncogene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 45, pp. 17420-5, (2008) (PubMed).
: "Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains." in: Genes & development, Vol. 22, Issue 4, pp. 528-42, (2008) (PubMed).
: "Parafibromin immunoreactivity: its use as an additional diagnostic marker for parathyroid tumor classification." in: Endocrine-related cancer, Vol. 14, Issue 2, pp. 501-12, (2007) (PubMed).
: "Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo." in: Cell, Vol. 125, Issue 2, pp. 327-41, (2006) (PubMed).
: "BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling." in: Mechanisms of development, Vol. 124, Issue 1, pp. 59-67, (2006) (PubMed).
Aliases for HRPT2 抗体
cell division cycle 73 (CDC73) 抗体cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73) 抗体
cell division cycle 73 (Cdc73) 抗体
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) (cdc73) 抗体
cell division cycle 73 (cdc73) 抗体
parafibromin (Tsp_03925) 抗体
parafibromin (Tsp_04052) 抗体
parafibromin (Tsp_04125) 抗体
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