HRK 产品
(Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
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This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012].
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Featured HRK Categories
HRK 抗体
High quality antibodies with extensive validation data.
HRK ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Recommended HRK 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7243397
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
- (1)
Cat. No.
ABIN2559409
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Human, Pig, Rabbit
Application
WB
Validations
- (1)
Cat. No.
ABIN6743246
Quantity
100 μL
Datasheet
Datasheet
Recommended HRK ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1120325
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1120326
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1120327
Quantity
96 tests
Datasheet
Datasheet
Latest Publications for our HRK Products
: "High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia." in: Leukemia, Vol. 30, Issue 6, pp. 1273-81, (2016) (PubMed).: "Preclinical Anticancer Efficacy of BET Bromodomain Inhibitors Is Determined by the Apoptotic Response." in: Cancer research, Vol. 76, Issue 6, pp. 1313-9, (2016) (PubMed).
: "Frequent HRK inactivation associated with low apoptotic index in secondary glioblastomas." in: Acta neuropathologica, Vol. 110, Issue 4, pp. 402-10, (2005) (PubMed).
: "Physical and functional interaction between BH3-only protein Hrk and mitochondrial pore-forming protein p32." in: Cell death and differentiation, Vol. 11, Issue 7, pp. 771-81, (2004) (PubMed).
: "Up-regulation of Hrk, a regulator of cell death, in retinal ganglion cells of axotomized rat retina." in: Neuroscience letters, Vol. 318, Issue 2, pp. 77-80, (2002) (PubMed).
: "Interleukin 3-dependent activation of DREAM is involved in transcriptional silencing of the apoptotic Hrk gene in hematopoietic progenitor cells." in: The EMBO journal, Vol. 20, Issue 9, pp. 2286-92, (2001) (PubMed).
: "Cell death in the third millennium." in: Cell death and differentiation, Vol. 7, Issue 1, pp. 2-7, (2000) (PubMed).
Synonyms and alternative names related to HRK
harakiri, BCL2 interacting protein (HRK), harakiri, BCL2 interacting protein (contains only BH3 domain) (Hrk), harakiri, BCL2 interacting protein (Hrk), AI838259, Bid3, DP5, Dp5, HARAKIRI, harakiriProtein level used designations for HRK
- BCL2-interacting protein
- BH3-interacting domain-containing protein 3
- activator of apoptosis Hrk
- activator of apoptosis harakiri
- death protein 5
- neuronal death protein DP5
- BH3 interacting (with BCL2 family) domain, apoptosis agonist
- BH3 interacting domain 3
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