HNRNPK 产品
(Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
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This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference\; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized. [provided by RefSeq, Jul 2008].
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Featured HNRNPK Categories
HNRNPK 抗体
High quality antibodies with extensive validation data.
HNRNPK ELISA试剂盒
Reliable ELISA kits for a wide range of species.
HNRNPK 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HNRNPK 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (12)
Cat. No.
ABIN3022414
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (7)
Cat. No.
ABIN2855169
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF, IP
Validations
- (5)
Cat. No.
ABIN7127548
Quantity
100 μL
Datasheet
Datasheet
Recommended HNRNPK ELISA试剂盒
Product
Reactivity
Analytical Method
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Cat. No.
Quantity
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Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956515
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967386
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1136562
Quantity
96 tests
Datasheet
Datasheet
Recommended HNRNPK 蛋白
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Reactivity
Human
Source
Wheat germ
Validations
- (2)
- (1)
Cat. No.
ABIN1306879
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
- (1)
Cat. No.
ABIN1047168
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN2722924
Quantity
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Datasheet
Datasheet
Latest Publications for our HNRNPK Products
: "LAST, a c-Myc-inducible long noncoding RNA, cooperates with CNBP to promote CCND1 mRNA stability in human cells." in: eLife, Vol. 6, (2018) (PubMed).: "Heterogeneous nuclear ribonucleoprotein K is overexpressed and associated with poor prognosis in gastric cancer." in: Oncology reports, Vol. 36, Issue 2, pp. 929-35, (2016) (PubMed).
: "Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43." in: Human molecular genetics, Vol. 24, Issue 6, pp. 1655-69, (2015) (PubMed).
: "Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes." in: The Journal of cell biology, Vol. 208, Issue 5, pp. 613-27, (2015) (PubMed).
: "Anxiety-associated alternative polyadenylation of the serotonin transporter mRNA confers translational regulation by hnRNPK." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 28, pp. 11624-9, (2013) (PubMed).
: "Improvement of protein immobilization for the elaboration of tumor-associated antigen microarrays: application to the sensitive and specific detection of tumor markers from breast cancer sera." in: Biosensors & bioelectronics, Vol. 40, Issue 1, pp. 385-92, (2012) (PubMed).
: "Heterogeneous nuclear ribonucleoprotein k interacts with Abi-1 at postsynaptic sites and modulates dendritic spine morphology." in: PLoS ONE, Vol. 6, Issue 11, pp. e27045, (2011) (PubMed).
: "Identification of heterogeneous nuclear ribonucleoprotein K as a transactivator for human low density lipoprotein receptor gene transcription." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17789-97, (2010) (PubMed).
: "A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response." in: Cell, Vol. 142, Issue 3, pp. 409-19, (2010) (PubMed).
: "The importance of heterogeneous nuclear ribonucleoprotein K on cytochrome P450 2D2 gene regulation: its binding is reduced in Dark Agouti rats." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 37, Issue 8, pp. 1703-10, (2009) (PubMed).
Synonyms and alternative names related to HNRNPK
heterogeneous nuclear ribonucleoprotein K (HNRNPK), heterogeneous nuclear ribonucleoprotein K (Hnrnpk), heterogeneous nuclear ribonucleoprotein K S homeolog (hnrnpk.S), heterogeneous nuclear ribonucleoprotein K (hnrnpk), heterogeneous nuclear ribonucleoprotein K (LOC5565718), heterogeneous nuclear ribonucleoprotein k (CpipJ_CPIJ000130), heterogeneous nuclear ribonucleoprotein K (NGK_p0004), CSBP, Csbp, HNRPK, Hnrpk, hnrpk, KBBP, MGC75642, NOVA, TUNP, wu:fb37h02, wu:fi34c04, zgc:66162Protein level used designations for HNRNPK
- dC-stretch binding protein
- transformation upregulated nuclear protein
- dC stretch-binding protein
- hnRNP K
- heterogeneous nuclear ribonucleoprotein K
- heterogeneous nuclear ribonucleoprotein k
- hnRNP-K protein
- heterogeneous nuclear ribonucleoprotein K-like
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