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HNRNPD/AUF1 产品

(Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))

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This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008].

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Featured HNRNPD/AUF1 Categories

HNRNPD/AUF1 抗体

High quality antibodies with extensive validation data.

HNRNPD/AUF1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

HNRNPD/AUF1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HNRNPD/AUF1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (7)
Cat. No. ABIN7258580
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (16)
Cat. No. ABIN6141905
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (7)
Cat. No. ABIN7267632
Quantity 100 μL
Datasheet Datasheet

Recommended HNRNPD/AUF1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380451
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1743204
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1774109
Quantity 96 tests
Datasheet Datasheet

Recommended HNRNPD/AUF1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1779693
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (3)
  • (1)
Cat. No. ABIN1047165
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2722913
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our HNRNPD/AUF1 Products

Hwang, Wagley, Law, Wei, Loh et al.: "Phosphorylation of poly(rC) binding protein 1 (PCBP1) contributes to stabilization of mu opioid receptor (MOR) mRNA via interaction with AU-rich element RNA-binding protein 1 (AUF1) and poly A ..." in: Gene, Vol. 598, pp. 113-130, (2017) (PubMed).

Zhang, Xue, Zheng, Wang, Zhou, Jiao, Geng, Wu, Hannafon, Ding: "The superoxide dismutase 1 3'UTR maintains high expression of the SOD1 gene in cancer cells: The involvement of the RNA-binding protein AUF-1." in: Free radical biology & medicine, Vol. 85, pp. 33-44, (2015) (PubMed).

Subramaniam, Ooi, Hui: "Transcriptional down-regulation of IGFBP-3 in human hepatocellular carcinoma cells is mediated by the binding of TIA-1 to its AT-rich element in the 3'-untranslated region." in: Cancer letters, Vol. 297, Issue 2, pp. 259-68, (2010) (PubMed).

Kang, Chen, Kim, Kang, Park: "Regulation of the hTERT promoter activity by MSH2, the hnRNPs K and D, and GRHL2 in human oral squamous cell carcinoma cells." in: Oncogene, Vol. 28, Issue 4, pp. 565-74, (2009) (PubMed).

Dhakras, Hajarnis, Taylor, Curthoys: "cAMP-dependent stabilization of phosphoenolpyruvate carboxykinase mRNA in LLC-PK1-F+ kidney cells." in: American journal of physiology. Renal physiology, Vol. 290, Issue 2, pp. F313-8, (2006) (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).

Dempsey, Li, DePace, Bray-Ward, Maizels: "The human HNRPD locus maps to 4q21 and encodes a highly conserved protein." in: Genomics, Vol. 49, Issue 3, pp. 378-84, (1998) (PubMed).

Kajita, Nakayama, Aizawa, Ishikawa: "The UUAG-specific RNA binding protein, heterogeneous nuclear ribonucleoprotein D0. Common modular structure and binding properties of the 2xRBD-Gly family." in: The Journal of biological chemistry, Vol. 270, Issue 38, pp. 22167-75, (1995) (PubMed).

Synonyms and alternative names related to HNRNPD/AUF1

heterogeneous nuclear ribonucleoprotein D (HNRNPD), heterogeneous nuclear ribonucleoprotein D (Hnrnpd), heterogeneous nuclear ribonucleoprotein D (hnrnpd), heterogeneous nuclear ribonucleoprotein D L homeolog (hnrnpd.L), AUF1, Auf1, AUF1A, auf1a, C230004L04, Hnrnpd, HNRNPD, hnRNPD0, hnrnpd0, HNRPD, hnrpd, Hnrpd, P37, p37, wu:fa28b06, zgc:162951

Protein level used designations for HNRNPD/AUF1

  • ARE-binding protein AUFI, type A
  • heterogeneous nuclear ribonucleoprotein D0
  • hnRNP D0
  • AU-rich element RNA-binding factor 1
  • AU-rich element RNA-binding protein 1
  • RNA binding protein p45AUF1
  • heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
  • AUF1
  • p37 AUF1
  • RNA binding protein
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