HNF4A 产品
(Hepatocyte Nuclear Factor 4, alpha (HNF4A))
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The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012].
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Featured HNF4A Categories
HNF4A 抗体
High quality antibodies with extensive validation data.
HNF4A ELISA试剂盒
Reliable ELISA kits for a wide range of species.
HNF4A 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HNF4A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, RNAi
Validations
- (2)
- (7)
Cat. No.
ABIN561308
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (5)
Cat. No.
ABIN6256265
Quantity
100 μL
Datasheet
Datasheet
Recommended HNF4A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967367
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6963170
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Pig
Analytical Method
Quantitative
Validations
Cat. No.
ABIN779022
Quantity
96 tests
Datasheet
Datasheet
Recommended HNF4A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (2)
Cat. No.
ABIN2722902
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306855
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306853
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our HNF4A Products
: "In vitro Differentiation of Human TERT-Transfected Multi-Lineage Progenitor Cells (MLPC) into Immortalized Hepatocyte-Like Cells." in: Hepatic medicine : evidence and research, Vol. 12, pp. 79-92, (2020) (PubMed).: "Hepatic Differentiation of Marmoset Embryonic Stem Cells and Functional Characterization of ESC-Derived Hepatocyte-Like Cells." in: Hepatic medicine : evidence and research, Vol. 12, pp. 15-27, (2020) (PubMed).
: "Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice." in: Scientific reports, Vol. 7, Issue 1, pp. 8976, (2019) (PubMed).
: "Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression." in: Cell death & disease, Vol. 8, Issue 7, pp. e2944, (2018) (PubMed).
: "Protocatechuic acid inhibits hepatitis B virus replication by activating ERK1/2 pathway and down-regulating HNF4α and HNF1α in vitro." in: Life sciences, Vol. 180, pp. 68-74, (2017) (PubMed).
: "Hepatocyte nuclear factor-4 alpha in noise-induced cochlear neuropathy." in: Developmental neurobiology, Vol. 76, Issue 12, pp. 1374-1386, (2016) (PubMed).
: "Preventing Gut Leakiness and Endotoxemia Contributes to the Protective Effect of Zinc on Alcohol-Induced Steatohepatitis in Rats." in: The Journal of nutrition, Vol. 145, Issue 12, pp. 2690-8, (2016) (PubMed).
: "Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion." in: Nature medicine, Vol. 21, Issue 5, pp. 512-7, (2015) (PubMed).
: "Hepatocyte nuclear factor (HNF) 4α transactivation of cytochrome P450 (Cyp) 2d40 promoter is enhanced during pregnancy in mice." in: Biochemical pharmacology, Vol. 94, Issue 1, pp. 46-52, (2015) (PubMed).
: "Direct reprogramming of human fibroblasts to hepatocyte-like cells by synthetic modified mRNAs." in: PLoS ONE, Vol. 9, Issue 6, pp. e100134, (2014) (PubMed).
Synonyms and alternative names related to HNF4A
hepatocyte nuclear factor 4 alpha (HNF4A), hepatocyte nuclear factor 4 alpha (hnf4a), Hepatocyte nuclear factor 4 (Hnf4), hepatic nuclear factor 4, alpha (Hnf4a), hepatocyte nuclear factor 4, alpha (Hnf4a), hepatocyte nuclear factor 4, alpha (hnf4a), hepatocyte nuclear factor 4 alpha S homeolog (hnf4a.S), hepatocyte nuclear factor 4 alpha (Hnf4a), CG9310, dHNF-4, dHNF4, Dmel\\CG9310, DmHNF4, fb58h09, HNF-4, Hnf-4, HNF-4(D), HNF-4alpha, Hnf-4h, HNF4, Hnf4, hnf4, HNF4A, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, Hnf4alpha, id:ibd1279, MODY, MODY1, Nr2a1, NR2A1, nr2a1, NR2A4, NR2A21, TCF, Tcf14, TCF14, wu:fb58h09Protein level used designations for HNF4A
- hepatocyte nuclear factor 4 alpha
- hepatocyte nuclear factor 4, alpha
- hepatocyte nuclear factor 4-alpha-like
- hepatocyte nuclear factor 4-alpha
- CG9310-PA
- CG9310-PB
- CG9310-PD
- CG9310-PE
- Hnf4-PA
- Hnf4-PB
- Hnf4-PD
- Hnf4-PE
- hepatocyte nuclear factor 4
- hepatocyte nuclear factor 4 homologue
- HNF-4-alpha
- HNF4 alpha
- HNF4alpha10
- HNF4alpha11
- HNF4alpha12
- Nuclear receptor 2A1
- TCF-14
- nuclear receptor subfamily 2 group A member 1
- transcription factor 14
- transcription factor HNF-4
- alpha transcription factor 4
- hepatic nuclear factor 4, alpha
- HNF4alpha10/11/12
- hepatic nuclear factor 4 alpha
- hepatic nuclear factor 4
- NR2A1
- hepatic nuclear factor 4alpha
- nuclear receptor
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