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HMGCS2 产品

(3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

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The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].

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Featured HMGCS2 Categories

HMGCS2 抗体

High quality antibodies with extensive validation data.

HMGCS2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

HMGCS2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HMGCS2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN7257752
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN7265329
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7156004
Quantity 100 μg
Datasheet Datasheet

Recommended HMGCS2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Pig
Analytical Method Quantitative
Validations
Cat. No. ABIN779074
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method Quantitative
Validations
Cat. No. ABIN1049620
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method Quantitative
Validations
Cat. No. ABIN1049622
Quantity 96 tests
Datasheet Datasheet

Recommended HMGCS2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306820
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306818
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5505541
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our HMGCS2 Products

Huang, Li, Wang, Zhang, Yan, Li, Xing, Wu, Hu, Jia, Lin, Dang, Song, Gao, Zhang: "Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress." in: Cell research, Vol. 26, Issue 10, pp. 1112-1130, (2017) (PubMed).

Clara, Schumacher, Ramachandran, Fedele, Krieger, Langhans, Mansouri: "Metabolic Adaptation of the Small Intestine to Short- and Medium-Term High-Fat Diet Exposure." in: Journal of cellular physiology, Vol. 232, Issue 1, pp. 167-75, (2016) (PubMed).

Karimian Azari, Leitner, Jaggi, Langhans, Mansouri: "Possible role of intestinal fatty acid oxidation in the eating-inhibitory effect of the PPAR-? agonist Wy-14643 in high-fat diet fed rats." in: PLoS ONE, Vol. 8, Issue 9, pp. e74869, (2013) (PubMed).

Vilà-Brau, De Sousa-Coelho, Gonçalves, Haro, Marrero: "Fsp27/CIDEC is a CREB target gene induced during early fasting in liver and regulated by FA oxidation rate." in: Journal of lipid research, Vol. 54, Issue 3, pp. 592-601, (2013) (PubMed).

Vilà-Brau, De Sousa-Coelho, Mayordomo, Haro, Marrero: "Human HMGCS2 regulates mitochondrial fatty acid oxidation and FGF21 expression in HepG2 cell line." in: The Journal of biological chemistry, Vol. 286, Issue 23, pp. 20423-30, (2011) (PubMed).

Synonyms and alternative names related to HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (HMGCS2), 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (Hmgcs2), hydroxymethylglutaryl-CoA synthase (mvaS), hydroxymethylglutaryl-CoA synthase (CNC05080), hydroxymethylglutaryl-coa synthase (HMCS1), hydroxymethylglutaryl-CoA synthase (hgsA), hydroxymethylglutaryl-CoA synthase (MFER_RS00425), hydroxymethylglutaryl-CoA synthase (LOC100285783), 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2 (ECU10_0510), 3-hydroxy-3-methylglutaryl-CoA synthase 2 (Eint_100450), 3-hydroxy-3-methylglutaryl-CoA synthase 2 (Hmgcs2), 1300002P16, DDBDRAFT_0219349, DDBDRAFT_0219924, DDB_0219349, DDB_0219924, hmgCoA, Hmgcs1, mHS, Mt3h3mg

Protein level used designations for HMGCS2

  • 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)
  • HMG-CoA synthase
  • hydroxymethylglutaryl-CoA synthase, mitochondrial
  • 3-hydroxy-3-methylglutaryl coenzyme A synthase
  • 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
  • hydroxymethylglutaryl-CoA synthase 2
  • hydroxymethylglutaryl-CoA synthase, mitochondrial-like
  • hydroxymethylglutaryl-CoA synthase
  • hydroxymethylglutaryl-coa synthase
  • GRMZM2G106263
  • putative hydroxymethylglutaryl-CoA synthase family protein
  • 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2
  • 3-hydroxy-3-methylglutaryl-CoA synthase 2
  • 3-hydroxy-3-methylglutary-Coenzyme A synthase 2
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