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HMGCR 蛋白

(3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))
HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
HMGCR Protein (AA 700-860) (His tag) HMGCR Protein (AA 700-860) (His tag) HMGCR Protein (AA 700-860) (His tag) (ABIN7121607)

HMGCR 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

HMGCR Protein (AA 1-835) (GST tag) HMGCR Protein (AA 1-835) (GST tag) HMGCR Protein (AA 1-835) (GST tag) (ABIN1306814)

HMGCR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

HMGCR Protein (AA 638-887) (His tag) (ABIN7397588)

HMGCR 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % WB, SDS, Imm, PC

HMGCR 蛋白 by Origin

Find HMGCR 蛋白 for a variety of species such as anti-Human HMGCR, anti-Mouse HMGCR, anti-Rat HMGCR. The species listed below are among those available. Click on a link to go to the corresponding products.

HMGCR 蛋白 by Source

Here you will find HMGCR 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

HMGCR 蛋白 by 蛋白类型

Here you can find HMGCR 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

HMGCR 蛋白 by 应用范围

Find HMGCR 蛋白 validated for a specific application such as WB, ELISA, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular HMGCR 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121607
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306814
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7397588
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3111788
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3134765
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5709669
Quantity 100 μg
Datasheet Datasheet

Aliases for HMGCR 蛋白

3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) 蛋白
3-hydroxy-3-methylglutaryl-CoA reductase L homeolog (hmgcr.L) 蛋白
3-hydroxy-3-methylglutaryl-Coenzyme A reductase (Hmgcr) 蛋白
3-hydroxy-3-methylglutaryl-CoA reductase (Hmgcr) 蛋白
HMG Coenzyme A reductase (Hmgcr) 蛋白
3-hydroxy-3-methylglutaryl-CoA reductase b (hmgcrb) 蛋白
3H3M 蛋白
BcDNA:LD15354 蛋白
bro1 蛋白
bs32f05.y1 蛋白
CG10367 蛋白
Clb 蛋白
clb 蛋白
Dmel\\CG10367 蛋白
DmHMG-CoAr 蛋白
Hmg 蛋白
hmg-coa-r 蛋白
HMG-CoAR 蛋白
HmG-CoAR 蛋白
hmgc 蛋白
HMGCoAR 蛋白
HMGCoAr 蛋白
HMGCoARr 蛋白
HMGCR 蛋白
hmgcr 蛋白
hmgcr2 蛋白
HMGCR_Dm 蛋白
HMGR 蛋白
hmgrc 蛋白
im:6912716 蛋白
l(3)01152 蛋白
l(3)04684 蛋白
LDLCQ3 蛋白
Red 蛋白
zgc:110746 蛋白
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