HLA-C 抗体
(Major Histocompatibility Complex Class I C (HLA-C))
HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described [provided by RefSeq, Jul 2008].
recommended
recommended
recommended
HLA-C 抗体 by 适用
Find HLA-C 抗体 for a variety of species such as anti-Human HLA-C, anti-Mouse HLA-C, anti-Non-Human Primate HLA-C. The species listed below are among those available. Click on a link to go to the corresponding products.
HLA-C 抗体 by 应用范围
Find HLA-C 抗体 validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.
HLA-C 抗体 by 抗体来源
Find HLA-C 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
HLA-C 抗体 by 克隆形成能力
Find available monoclonal or polyclonal HLA-C 抗体. Click on a link to go to the corresponding products.
HLA-C 抗体 by 克隆
Find HLA-C 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
HLA-C 抗体 by 标记
Find HLA-C 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular HLA-C 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7434662
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN7155625
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7155571
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ICC, IHC (p)
Validations
- (5)
Cat. No.
ABIN3043843
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7426466
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7155567
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN516469
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Non-Human Primate
Application
IP, FACS
Validations
- (2)
Cat. No.
ABIN7505980
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Non-Human Primate
Application
FACS
Validations
- (2)
Cat. No.
ABIN7505981
Quantity
100 tests
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7155626
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN516468
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Dog, Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6748176
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
Cat. No.
ABIN7155574
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
Cat. No.
ABIN7155572
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our HLA-C 抗体
: "The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression. ..." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 14, pp. 3366-3376, (2018) (PubMed).: "Influence of HLA-C expression level on HIV control. ..." in: Science (New York, N.Y.), Vol. 340, Issue 6128, pp. 87-91, (2013) (PubMed).
: "Reappraisal of the relationship between the HIV-1-protective single-nucleotide polymorphism 35 kilobases upstream of the HLA-C gene and surface HLA-C expression." in: Journal of virology, Vol. 85, Issue 7, pp. 3367-74, (2011) (PubMed).
: "TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide." in: Current biology : CB, Vol. 8, Issue 1, pp. 1-10, (1998) (PubMed).
Aliases for HLA-C 抗体
major histocompatibility complex, class I, C (HLA-C) 抗体D6S204 抗体
HLA-JY3 抗体
HLC-C 抗体
PSORS1 抗体
您还需要查找其他产品吗？
You are here:
